John G. Laffey on Muck Rack

John G. Laffey

Toronto
As seen in: JAMA: Journal of the American Medical Association, Journal of Intensive Care, EClinicalMedicine, The Lancet, Healio, European Respiratory Journal, European Respiratory Review, Physician's Weekly, European Journal of Vascular and Endovascular Surgery, Annals of Vascular Surgery
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Articles

Efficacy of inhaled nebulised unfractionated heparin to prevent intubation or death in hospitalised patients with COVID-19: an investigator-initiated international meta-trial of randomised clinical studies

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By Sarah J. Valle, Marcus J. Schultz, Amsterdam UMC, John G. Laffey
| EClinicalMedicine Verified
Keywords COVID-19 ARDS Inhaled heparin Nebulised heparin Unfractionated heparin SARS-CoV-2 Respiratory failure Pandemic Randomised trial Meta-trial Intubation Mortality Evidence before this study Inhaled nebulised unfractionated heparin (UFH) has been shown to improve outcomes and has been shown to be safe in experimental and clinical studies of acute lung injury and ARDS.
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Chunking: Let's Break It Down

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By John G. Laffey
| datastax.com
As you adopt AI practices, one of the more challenging aspects of getting data AI-ready is “chunking.”  Chunking is, as the name suggests, breaking down large blocks of text into smaller segments. Each chunk is then vectorized, stored, and indexed. Any type of data can be chunked: text documents, images, sound files. For clarity, we’ll stick to text chunking, but the theory and process is the same for any type of data. Chunking is a necessary step in vectorizing data for many reasons.
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Mechanical ventilation in patients with cardiogenic pulmonary edema: a sub-analysis of the LUNG SAFE study - Journal of Intensive Care

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By Laura Amado-Rodríguez, Giacomo Bellani, Tài Pham, Eddy Fan, Fabiana Madotto, John G. Laffey, Guillermo M. Albaiceta, Raquel Rodríguez-Garcia
| Journal of Intensive Care Verified
Background Patients with acute respiratory failure caused by cardiogenic pulmonary edema (CPE) may require mechanical ventilation that can cause further lung damage. Our aim was to determine the impact of ventilatory settings on CPE mortality. Methods Patients from the LUNG SAFE cohort, a multicenter prospective cohort study of patients undergoing mechanical ventilation, were studied.
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