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Articles by John Gregson
Genoveva ( 1953 )
"Genevieve" - 1h 26min - Reino Unido ComediaAutomovilismoRelaciones de pareja Puntúala Insertar Alan McKim, un joven abogado, decide participar en el Rally Anual de coches antiguos de Londres a Brighton con su Darraq de 1904 llamado Genoveva. Wendy, su esposa, opina que la carrera es una tontería y un símbolo de inmadurez. Ambrose Claverhouse, amigo del joven matrimonio, decide competir con Alan en el Rally: Rosalind Peters, antigua novia de Ambrose, será su acompañante.
John Batley obituary: shooting writer and GTA director
5 April 1940 to 1 September 2026 The sporting world has lost one of the last of the old-school greats with the death on 1 September of John Batley, shooting writer, pigeon shooter, fisherman, businessman, car enthusiast, wine connoisseur, former director of the Gun Trade Association, family man, friend and all-round bon oeuf. I knew John for more than 30 years, having met him when I joined Shooting Times in the early 1990s.
Social Harm and Neoliberalism
This book links criminological, political, moral, and philosophical issues to offer a deeper understanding of the problem of social harm within the neoliberal environment. Illustrated through case studies, John Gregson shows that social harms are a problem created not only by politics or economics, states or corporations, but also by the individualism that neoliberal societies encourage.
Studies in Social Harm
Series Editors: Christina Pantazis, University of Bristol, UK and Simon Pemberton, University of Birmingham, UK “This series considers what matters most. Our value system is out of kilter. We imprison people, mostly the poorest, often for committing minor crimes, including not being able to pay back debts. We frequently laud those who can commit the most harm as wealth creators.
Hierarchical Composite Outcomes and Win Ratio Methods in Cardiovascular Trials: A Review and Consequent Guidance
Get full access to this article View all available purchase options and get full access to this article. Supplemental Material File (circ-2024-070251-s01.pdf) Appendix Tables S1 and S2 References 1. Pocock SJ, Ariti CA, Collier TJ, Wang D. The win ratio: a new approach to the analysis of composite endpoints in clinical trials based on clinical priorities. Eur Heart J. 2012;33:176–182. doi: 10.1093/eurheartj/ehr352 2. Finkelstein DM, Schoenfeld DA.
Competing Risks in Clinical Trials: Do They Matter and How Should We Account for Them?
References 1. "The analysis of survival data in nephrology: basic concepts and methods of Cox regression". Kidney Int . 2008;74:705-709. 2. "A proportional hazards model for the subdistribution of a competing risk". J Am Stat Assoc . 1999;94:496-509. 3. "Applying Cox regression to competing risks". Biometrics . 1995;51:524-532. 4. "Relaxing the independent censoring assumption in the Cox proportional hazards model using multiple imputation". Stat Med . 2014;33:4681-4694. 5. "R package InformativeCensoring.
winratiotest: A command for implementing the win ratio and stratified win ratio in Stata
winratiotest: A command for implementing the win ratio and stratified win ratio in Stata Autores: John Gregson, João Pedro Ferreira, Tim Collier Localización: The Stata journal, ISSN 1536-867X, Vol. 23, Nº. 3, 2023, págs. 835-850 Idioma: inglés Enlaces Texto completo Resumen The win ratio is a statistical method most commonly used for ana- lyzing composite outcomes in clinical trials.
Non-proportional hazards demystified: Why they matter for planning and interpreting clinical trials
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Recurrent Events in Cardiovascular Trials: JACC State-of-the-Art Review
1. "Comparison of time-to-first event and recurrent-event methods in randomized clinical trials". Circulation . 2018;138:570-577. 2. "Time to move on from “time-to-first”: Should all events be included in the analysis of clinical trials?"Eur Heart J . 2012;33:2764-2765. 3. "Sotagliflozin in patients with diabetes and chronic kidney disease". N Engl J Med . 2021;384:129-139. 4. "Sotagliflozin in patients with diabetes and recent worsening heart failure". N Engl J Med . 2021;384:117-128. 5.
Socioeconomic Deprivation: An Important, Largely Unrecognized Risk Factor in Primary Prevention of Cardiovascular Disease
Originally publishedCirculation. 2022;0:10.1161/CIRCULATIONAHA.122.060042 Abstract BACKGROUND: Socioeconomic deprivation is associated with higher cardiovascular morbidity and mortality. Whether deprivation status should be incorporated in more cardiovascular risk estimation scores remains unclear. This study evaluates how socioeconomic deprivation status affects the performance of 3 primary prevention cardiovascular risk scores.
Optimised medical therapy alone versus optimised medical therapy plus revascularisation for asymptomatic or low-to-intermediate risk symptomatic carotid stenosis (ECST-2): 2-year interim results of a multicentre randomised trial
ArticlesVolume 24, Issue 5p389-399Open access aDepartment of Vascular Surgery, UMC Utrecht, Utrecht, Netherlands bDepartment of Neurology, Amsterdam UMC, location AMC, Amsterdam, Netherlands cStroke Research Centre, Department of Brain Repair and Rehabilitation, UCL Queen Square Institute of Neurology, University College London, London, UK dDepartment of Medical Statistics, London School of Hygiene & Tropical Medicine, London, UK eDepartment of Engineering for Innovation Medicine, University...
Moderate excess alcohol consumption and adverse cardiac remodelling in dilated cardiomyopathy
Heart failure and cardiomyopathies Moderate excess alcohol consumption and adverse cardiac remodelling in dilated cardiomyopathy http://orcid.org/0000-0003-2262-4626Upasana Tayal1,2, John Gregson3, Rachel Buchan1,2, Nicola Whiffin1,2, Brian P Halliday1,2, Amrit Lota1,2, Angharad M Roberts4, A John Baksi1,2, Inga Voges2, Julian W E Jarman1,2, Resham Baruah2, Michael Frenneaux2, John G F Cleland1,5, Paul Barton1,2, Dudley J Pennell1,2, James S Ware1,2,4, Stuart A Cook4,6, Sanjay K Prasad1,2 1...
Long Term Restenosis Rate After Carotid Endarterectomy: Comparison of Three Surgical Techniques and Intra-Operative Shunt Use
Objective Closure of the artery during carotid endarterectomy (CEA) can be done with or without a patch, or performed with the eversion technique, while the use of intra-operative shunts is optional. The influence of these techniques on subsequent restenosis is uncertain. Long term carotid restenosis rates and risk of future ipsilateral stroke with these techniques were compared.
Moderate excess alcohol consumption and adverse cardiac remodelling in dilated cardiomyopathy
Heart failure and cardiomyopathies Moderate excess alcohol consumption and adverse cardiac remodelling in dilated cardiomyopathy http://orcid.org/0000-0003-2262-4626Upasana Tayal1,2, John Gregson3, Rachel Buchan1,2, Nicola Whiffin1,2, Brian P Halliday1,2, Amrit Lota1,2, Angharad M Roberts4, A John Baksi1,2, Inga Voges2, Julian W E Jarman1,2, Resham Baruah2, Michael Frenneaux2, John G F Cleland1,5, Paul Barton1,2, Dudley J Pennell1,2, James S Ware1,2,4, Stuart A Cook4,6, Sanjay K Prasad1,2...
Implications of Biomarker Discordance After Coronary Artery Revascularization: The EXCEL Trial
1. Gregson J., Stone G.W., Ben-Yehuda O., et al. "Implications of alternative definitions of peri-procedural myocardial infarction after coronary revascularization". J Am Coll Cardiol 2020;76:1609-1621. 2. Lum G., Solarz D.E., Farney L. "False positive cardiac troponin results in patients without acute myocardial infarction". Lab Med 2006;37:546-550. 3. Malasky B.R., Alpert J.S. "Diagnosis of myocardial injury by biochemical markers: problems and promises". Cardiol Rev 2002;10:306-317.
Myocardial remodelling after withdrawing therapy for heart failure in patients with recovered dilated cardiomyopathy: insights from TRED‐HF
Abstract Aims To characterize adverse ventricular remodelling after withdrawing therapy in recovered dilated cardiomyopathy (DCM). Methods and results TRED‐HF was a randomized controlled trial with a follow‐on single‐arm cross‐over phase that examined the safety and feasibility of therapy withdrawal in patients with recovered DCM over 6 months.
Arterial Spin Labeling MRI in Carotid Stenosis: Arterial Transit Artifacts May Predict Symptoms
Summary Arterial transit artifacts at arterial spin labeling MRI were the only factor associated with recent ischemic symptoms in participants with carotid stenosis. Key Results ■ Arterial transit artifact (ATA) was present in 16 of 16 participants with stenosis greater than 70% (P < .001) and was associated with absence of anterior communicating artery (11 of 16 patients; P = .003).
Implications of Alternative Definitions of Peri-Procedural Myocardial Infarction After Coronary Revascularization
Journal of the American College of Cardiology Original Investigation John Gregson, Gregg W. Stone, Ori Ben-Yehuda, Björn Redfors, David E. Kandzari, Marie-Claude Morice, Martin B. Leon, Ioanna Kosmidou, Nicholas J. Lembo, W. Morris Brown iii, Dimitri Karmpaliotis, Adrian P. Banning, Jose Pomar, Manel Sabaté, Charles A. Simonton, Ovidiu Dressler, Arie Pieter Kappetein, Joseph F. Sabik iii, Patrick W. Serruys and Stuart J. Pocock This article requires a subscription or purchase to view the full text.
Effect of supplemental nutrition in pregnancy on offspring’s risk of cardiovascular disease in young adulthood: Long-term follow-up of a cluster trial from India
Loading metrics Open Access Peer-reviewed Research Article Sanjay Kinra , John Gregson, Poornima Prabhakaran, Vipin Gupta, Gagandeep Kaur Walia, Santhi Bhogadi, Ruby Gupta, Aastha Aggarwal, Poppy Alice Carson Mallinson, Bharati Kulkarni, Dorairaj Prabhakaran, George Davey Smith, K. V. Radha Krishna, Shah Ebrahim, Hannah Kuper, [ ...
Impact of tricuspid regurgitation on survival in patients with heart failure: a large electronic health record patient‐level database analysis
Research Article David Messika‐Zeitoun Corresponding Author E-mail address: dmessika‐zeitoun@ottawaheart.ca University of Ottawa Heart Institute, Ottawa, Canada Corresponding author. University of Ottawa Heart Institute, 40 Rue Ruskin Street, Ottawa, ON K1Y 4W7, Canada.
Comparison of Propensity Score Methods and Covariate Adjustment
Journal of the American College of Cardiology Review Topic of the Week Markus C. Elze, John Gregson, Usman Baber, Elizabeth Williamson, Samantha Sartori, Roxana Mehran, Melissa Nichols, Gregg W. Stone and Stuart J. Pocock Author + information Markus C. Elze, PhDa,b, John Gregson, PhDa, Usman Baber, MD, PhDc, Elizabeth Williamson, PhDa, Samantha Sartori, PhDc, Roxana Mehran, MD, PhDc, Melissa Nichols, PhDd,e, Gregg W. Stone, MD, PhDd,e and Stuart J.
Is agricultural engagement associated with lower incidence or prevalence of cardiovascular diseases and cardiovascular disease risk factors? A systematic review of observational studies from low- and middle-income countries
Loading metrics Open Access Peer-reviewed Research Article Tina B. Sørensen , Mika Matsuzaki, John Gregson, Sanjay Kinra, Suneetha Kadiyala, Bhavani Shankar, Alan D. Dangour Tina B. Sørensen, Mika Matsuzaki, John Gregson, Sanjay Kinra, Suneetha Kadiyala, Bhavani Shankar, Alan D.
Nonproportional Hazards for Time-to-Event Outcomes in Clinical Trials
Journal of the American College of Cardiology JACC Review Topic of the Week John Gregson, Linda Sharples, Gregg W. Stone, Carl-Fredrik Burman, Fredrik Öhrn and Stuart Pocock This article requires a subscription or purchase to view the full text. If you are a subscriber or member, click the login link or the subscribe link in the top menu above to access this article. Author + information John Gregson, PhDa,∗ (John.gregson{at}lshtm.ac.uk), @GreggWStone, Linda Sharples, PhDa, Gregg W.
Mixtape Week - KEXP
Mixtapes are time capsules that communicate a multitude of emotions: Love, despair, joy. They are the soundtracks to important moments in our lives and a way to share those moments, along with the bands and artists you love. Since the advent of digital technology, tapes have given way to CDs, CDs have given way to playlists, all of which share human curation and visual representation in a meaningful manner--and that's something to celebrate. At KEXP we create new mixes every day.
Restenosis and risk of stroke after stenting or endarterectomy for symptomatic carotid stenosis in the International Carotid Stenting Study (ICSS): secondary analysis of a randomised trial
In this secondary analysis of ICSS, the long-term risk of moderate or higher (≥50%) restenosis, or occlusion of the carotid artery, was significantly higher after stenting than after endarterectomy. As previously reported,9x9Bonati, LH, Dobson, J, Featherstone, RL et al. Long-term outcomes after stenting versus endarterectomy for treatment of symptomatic carotid stenosis: the International Carotid Stenting Study (ICSS) randomised trial. Lancet.
HIV-1 drug resistance before initiation or re-initiation of first-line antiretroviral therapy in low-income and middle-income countries: a systematic review and meta-regression analysis - The Lancet Infectious Diseases
Pretreatment HIV drug resistance can be detected in people naive to antiretroviral drugs who are initiating ART or people who are initiating or re-initiating first-line ART who have had previous exposure. Pretreatment drug resistance can be either transmitted or acquired drug resistance, or both.
Child obesity cut-offs as derived from parental perceptions: cross-sectional questionnaire
AbstractBackground Overweight children are at an increased risk of premature mortality and disease in adulthood. Parental perceptions and clinical definitions of child obesity differ, which may lessen the effectiveness of interventions to address obesity in the home setting.
Genetic invalidation of Lp-PLA2 as a therapeutic target: Large-scale study of five functional Lp-PLA2-lowering alleles
Darapladib, a potent inhibitor of lipoprotein-associated phospholipase A (Lp-PLA ), has not reduced risk of cardiovascular disease outcomes in recent randomized trials. We aimed to test whether Lp-PLA enzyme activity is causally relevant to coronary heart disease.
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