Milton Packer on Muck Rack

Milton Packer

As seen in: MedPage Today, Arthritis & Rheumatology, Color Research & Application, Nature, Wiley, Wiley Online Library, heart, The BMJ, JAMA (The Journal of the American Medical Association), JAMA: Journal of the American Medical Association, JAMA Cardiology and
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Articles

Excess and Dysfunctional Fat as a Primary Driver of Heart Failure With Preserved Ejection Fraction: From Institutional Recognition to Clinical Integration

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By Milton Packer, Jennifer Ho, Mark C. Petrie
| JACC (Journal of the American College of Cardiology)
JACC Journals › JACC: Heart Failure › Archives › Just Accepted Methodology and Mechanisms Corner : JACC: Heart Failure Just Accepted Heart failure with preserved ejection fraction (HFpEF) is defined as signs and symptoms of heart failure (related to increased left ventricular filling pressures at rest or during exercise) in a patient with an ejection fraction ≥50%, following the exclusion of other disorders (ie, HFpEF mimics), which include cardiac amyloidosis, valvular heart disease (eg,...
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AHA 25: HFpEF as an Adipose Tissue Disorder: Implications for Diagnosis and Therapy

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By Harriette Van Spall, Milton Packer, Emily Lau, Stephen Nicholls 
| RadcliffeCardiology.com
Video Published: Likes: 0 Average (ratings) AHA Scientific Sessions 2025 - Dr Milton Packer (Baylor University Medical Center, US) joins us to discuss his novel unifying hypothesis that heart failure with preserved ejection fraction arises primarily from visceral adipose tissue dysfunction and altered adipokine signaling, rather than as a heterogeneous disorder driven by multiple comorbidities. Interview Questions: Can you explain the core premise of the adipokine hypothesis?
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Chronic Kidney Disease in Patients With Heart Failure With a Preserved Ejection Fraction: The Underlying Role of Visceral Adiposity

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By Milton Packer, Jeffrey M. Testani, Javed Butler, Faiez Zannad
| JACC (Journal of the American College of Cardiology)
JACC Journals › JACC › Archives › Vol. 86 No. 20 Special Communication : JACC Volume 86, Number 20 Heart failure and a preserved ejection fraction (HFpEF) and chronic kidney disease can coexist,1 and chronic kidney disease has been proposed as a distinct pathway through which HFpEF may develop.2 However, the nature of and the potential mechanisms that may underlie a HFpEF–kidney relationship have not been critically evaluated.
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