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Fgf signaling controls the telencephalic distribution of Fgf-expressing progenitors generated in the rostral patterning center

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By Renée V Hoch, Jeffrey A Clarke, John LR Rubenstein, Renée V, John LR
| neuraldevelopment.com
Background The rostral patterning center (RPC) secretes multiple fibroblast growth factors (Fgfs) essential for telencephalon growth and patterning. Fgf expression patterns suggest that they mark functionally distinct RPC subdomains. We generated Fgf8 CreER and Fgf17 CreER mice and used them to analyze the lineages of Fgf8- versus Fgf17-expressing RPC cells.
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