John Pietro

1. Introduction Ochronosis, named in reference to the Greek word “ochre” meaning “earthy” or “yellowed in appearance,” is a rare disorder that presents primarily as discolored blue-black or grey-blue pigmentation of the skin, cartilage of the ears, and sclerae [1]. Endogenous ochronosis is synonymous with alkaptonuria (AKU, OMIM 203500), which has also been called “black urine disease,” since the urine collected from those affected turns black upon standing.

Donald Trump has reportedly decided that he won’t be attending the first Republican debate next Wednesday and will counter-program by sitting down for an interview with Tucker Carlson. (The choice is a double middle-finger: one from Trump to the RNC, another from Carlson to his former network.) In the end, the question of whether Trump would show up or not became a fairly low-stakes question. A candidate with a lead as large as his just doesn’t need to sweat decisions like this all that much.