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Articles by John Sheppard
Updated ocular pharmacology for noninfectious Uveitis: a comprehensive expert review
ABSTRACT INTRODUCTION Uveitis encompasses a heterogeneous group of inflammatory disorders affecting the iris, ciliary body, and choroid and remains a leading cause of preventable blindness worldwide. Although corticosteroids have historically served as first-line therapy, long-term exposure is associated with ocular morbidity.
Computer Science > Artificial Intelligence
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Association for Research in Vision and Ophthalmology
Post hoc analysis finds quick response to Xiidra Add topic to email alerts Receive an email when new articles are posted on Please provide your email address to receive an email when new articles are posted on . Subscribe We were unable to process your request. Please try again later. If you continue to have this issue please contact customerservice@slackinc.com. Back to Healio Key takeaways: At day 84, 55.3% of patients achieved a reduction in eye dryness of 60% or more.
Association for Research in Vision and Ophthalmology
Post hoc analysis finds quick response to Xiidra Add topic to email alerts Receive an email when new articles are posted on Please provide your email address to receive an email when new articles are posted on . Subscribe We were unable to process your request. Please try again later. If you continue to have this issue please contact customerservice@slackinc.com. Back to Healio Key takeaways: At day 84, 55.3% of patients achieved a reduction in eye dryness of 60% or more.
Computer Science > Machine Learning
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VIDEO: Expert highlights available, upcoming therapies for neurotrophic keratitis
Disclosures: Sheppard reports having financial disclosures for 1-800-DOCTORS, AbbVie, Aerie, Alcon, Aldeyra, Allergan, Alphaeon/Strathspey Crown, ArcScan, Aurion, Avedro, Bausch + Lomb, BioLayer, BioTissue/TissueTech, Brill Engines, Bruder Healthcare Company, Claris Bio, Clearside, Clearview, Clementia, Dompé, EcoR1, Eleven Optical, Epion, Eyedetec, EyeGate, EyeRx Research, Eyevance, Fortress, Glaukos, Hovione, Imprimis, Insite, Inspire/Merck, Isis, Ionis, Johnson &...
VIDEO: Noncontact esthesiometer quantifies neurotrophic keratitis
Ask a clinical question and tap into Healio AI's knowledge base. WAIKOLOA, Hawaii — In this expert perspective from Hawaiian Eye 2026, John D. Sheppard, MD, MMSc, FACS, discusses a corneal esthesiometer developed by Brill Engines to detect neurotrophic keratitis. According to Sheppard, of Virginia Eye Consultants, the noncontact esthesiometer can be placed on a slit lamp and reach quantitative levels up to 6° of sensitivity.
VAAS: Vision-Attention Anomaly Scoring for Image Manipulation Detection in Digital Forensics
arXivLabs is a framework that allows collaborators to develop and share new arXiv features directly on our website. Both individuals and organizations that work with arXivLabs have embraced and accepted our values of openness, community, excellence, and user data privacy. arXiv is committed to these values and only works with partners that adhere to them. Have an idea for a project that will add value for arXiv's community? Learn more about arXivLabs.
The Doors Are Open 1968 1080p BluRay DD5.1 HEVC x265-RMTeam
snickerdoodle: @waanaabe Nope. It's not on other release or torrent sites, either. My guess is some error with the ... waanaabe: There is still no episode 2 of The Big Fuck Up? Ehsan: Wrong episode , This is s37e10 , not episode 11 ppoo: @Admin Please, can you add "IT.Welcome.to.Derry.S01E08.720p.WEB.H264-JFF.mkv" ?? snickerdoodle: Home for Christmas - Season 1 Norwegian and English audio English subs for Norwegian audio trackSome...
The Doors Are Open 1968 1080p BluRay x264-OFT
snickerdoodle: @waanaabe Nope. It's not on other release or torrent sites, either. My guess is some error with the ... waanaabe: There is still no episode 2 of The Big Fuck Up? Ehsan: Wrong episode , This is s37e10 , not episode 11 ppoo: @Admin Please, can you add "IT.Welcome.to.Derry.S01E08.720p.WEB.H264-JFF.mkv" ?? snickerdoodle: Home for Christmas - Season 1 Norwegian and English audio English subs for Norwegian audio trackSome...
[2511.04124] Decomposable Neuro Symbolic Regression
arXivLabs is a framework that allows collaborators to develop and share new arXiv features directly on our website. Both individuals and organizations that work with arXivLabs have embraced and accepted our values of openness, community, excellence, and user data privacy. arXiv is committed to these values and only works with partners that adhere to them. Have an idea for a project that will add value for arXiv's community? Learn more about arXivLabs.
Effects of Eicosapentaenoic Acid vs Eicosapentaenoic/Docosahexaenoic Acids on Cardiovascular Mortality: Meta-Analysis of Clinical Trials
Purified eicosapentaenoic acid (EPA) and mixed eicosapentaenoic/docosahexaenoic acids (EPA/DHA), the major constituents of fish oil, are omega-3 (n-3) polyunsaturated fatty acids (PUFAs) of interest for their antiatherogenic effects in the prevention of cardiovascular disease (CVD).1 Several randomized clinical trials (RCTs) have studied the efficacy of EPA and EPA/DHA on reducing cardiovascular endpoints, including myocardial infarction (MI), stroke, and CVD-attributable mortality.
Reproxalap Improves Ocular Redness, Tear Production, and Symptoms in a Pivotal Dry Eye Disease Chamber Trial
Research ArticleArticles in Press100938Open access 1University of California, Irvine, CA 2OCLI Vision, Garden City, NY 3Eastern Virginia Medical School, Norfolk, VA 4The Eye Center of Columbus, Columbus, Ohio 5Aldeyra Therapeutics, Lexington, MA Publication History: Received March 17, 2025; Revised August 28, 2025; Accepted August 29, 2025; Published online September 10, 2025 DOI: 10.1016/j.xops.2025.100938 External LinkAlso available on ScienceDirect External Link Copyright: © 2025 Published...
10 Недорогих выделенных VPS-серверов в РФ — John Sheppard на vc.ru
С развитием цифровых технологий всё больше компаний и частных разработчиков сталкиваются с необходимостью аренды надёжного сервера. Выделенные серверы — это основа инфраструктуры любого онлайн-проекта, будь то интернет-магазин, корпоративный сайт или приложение. Выбор провайдера с дата-центром в России позволяет добиться низкой задержки, высокой скорости работы и оперативной поддержки. В этой статье я собрал 10 недорогих решений для аренды выделенного VPS.
Зарубежные VPS с оплатой из России - Делюсь подборкой — John Sheppard на vc.ru
После того как многие западные хостинги ограничили оплату для пользователей из России, найти иностранные VPS с удобной системой расчётов стало заметно сложнее. Особенно если важна оплата в рублях из РФ. Я изучил рынок и собрал подборку зарубежных провайдеров, у которых всё ещё можно арендовать VPS с зарубежной локацией и при этом обойтись без VPN. Fornex — европейский провайдер с серверами в Германии, Нидерландах и Швейцарии.
10 Дешёвых VPS в Европе с оплатой в рублях — John Sheppard на vc.ru
После 2022 года у многих владельцев сайтов в России возник острый вопрос: где арендовать VPS, чтобы он был стабильным, находился в Европе, поддерживал оплату в рублях и предлагал русскоязычную техническую поддержку? Многие западные провайдеры изменили свою политику, однако нашлись те, кто продолжает работать с российскими клиентами — без блокировок, с привычными способами оплаты и качественным сервисом.
7 Нейросетей подходящих для Телефона Android и IOS — John Sheppard на vc.ru
В наше время нейросети — это уже не хайп, а обыденность. Потребность в нейросетях есть у многих пользователей Android и iOS. Пользоваться нейросетями с телефона иногда очень удобно, а порой — даже необходимо. В общем, я решил сделать подборку нейросетей, которые подходят для телефона и не требуют никаких VPN. Сперва пару мощных Телеграм ботов с AI. Они работают без регистрации, что делает их особенно удобными. 1) SyntxAI Bot — многофункциональный бот с нейросетями.
Как собрать семантическое ядро автоматически с помощью нейросетей? — SEO на vc.ru
Всем привет! В данной статье речь пойдёт о полной автоматизации сбора семантического ядра. Ещё не так давно нейросети плохо справлялись с этой задачей, но сегодня ситуация изменилась. Поделюсь своим опытом и подробно всё расскажу. Надеюсь, будет интересно и полезно. Перейдём сразу к делу. В общем тут все очень просто. Заходим в Вордстат и скачиваем вариации фраз по нужному нам запросу. Открываем файл на своем ПК и копируем фразы. Но копируем не все фразы, а по 50-100 шт. Почему так?
Интересное из книги "Покупатель на крючке" для разработчиков Saas — Офтоп на vc.ru
Было время прочитал данную книгу. В целом мне понравилось. Выписал для себя самое интересное. Спустя время решил поделиться. Надеюсь и вам будет полезно. 1. Есть 2 вида продуктов: витамины и болеутоляющие. Витамины приносят пользу, а болеутоляющие избавляют людей от боли. 2. Продукт должен быть достаточно лёгким. Чем меньше действий нужно совершить клиенту для получения вознаграждения, тем больше у него мотивации. В противном случае мотивация падает. 3.
Цитаты из книги для стартаперов "Стратегия голубого океана" - Самое интересное — Офтоп на vc.ru
Всем привет! Было время прочитал данную книгу. В целом, мне понравилось. Выписал для себя самое основное, но и вот, спустя время решил поделиться. 1. Отказ от факторов, которые служат предметом конкуренции. 2. Какие продукты в погоне за конкурентами становятся излишне сложными? В такой ситуации компании начинают предоставлять клиентам избыточные услуги, увеличивая свои издержки, не получая отдачи. Отказ от таких продуктов. 3. На какие компромиссы идут потребители? Нужно избавить клиентов от этого. 4.
Как собрать поисковые ключевые слова быстро? Мануал — John Sheppard на vc.ru
Сбор семантического ядра — это первый и один из самых важных этапов в SEO и контекстной рекламе. Он определяет, по каким запросам ваш сайт или реклама будут видны в поиске, насколько вы попадете в ожидания аудитории и какова будет конверсия. Многие до сих пор собирают ключи вручную или в Excel с копированием из Wordstat, но это уже прошлый век. Сегодня этот процесс можно автоматизировать и ускорить в разы.
5 Сервисов для автоподбора ключевых SEO-фраз — SEO на vc.ru
Автоматизация в SEO — сегодня это не роскошь, а необходимость. Особенно это касается сбора и обработки семантического ядра. Я собрал 5 полезных инструментов, которые помогут быстро и качественно подобрать ключевые фразы для сайта или рекламной кампании. Telegram-бот для автоматического сбора семантики. Semantix Bot — это удобный и современный телеграм-бот, который за считанные минуты собирает и очищает семантическое ядро по любым вашим критериям.
Насколько часто сайт посещают поисковые роботы? Как узнать реальную картину — SEO на vc.ru
Понимание поведения поисковых ботов (краулеров) — важная часть оптимизации сайта под поисковые системы. От того, как часто и какие страницы сканируют Googlebot, YandexBot или Bingbot, зависит, насколько быстро новые материалы попадут в индекс, а также то, как будет ранжироваться ваш сайт в выдаче. Однако, несмотря на критическую важность этого аспекта SEO, отслеживание активности ботов — задача, которая многим кажется сложной, но на самом деле это не так.
5 Сервисов для анализа конкуренции ключевых слов — SEO на vc.ru
Когда я только начал заниматься SEO, довольно быстро понял: просто собрать список ключевых слов недостаточно. Важно понимать, насколько сложно будет по ним продвинуться. Частотность может быть высокой, но без понимания конкуренции можно потратить массу времени — и не получить результата. Поэтому я использую сервисы, которые помогают быстро оценить обстановку по каждому запросу. Ниже — проверенные мной инструменты, которые реально помогают в работе.
DMF Diadromous Project Looks to Future Technologies for Monitoring Fish Populations
Monitoring alewife and blueback herring abundance during their annual spring spawning migrations from ocean waters to freshwater habitats is a vital component to the management of these species (collectively referred to as “river herring”). Currently, between 40 to 50 streams are monitored for river herring passage in coastal Massachusetts each year.
Correction: Popoola, G.; Sheppard, J. Investigating and Mitigating the Performance-Fairness Tradeoff via Protected-Category Sampling. Electronics 2024, 13, 3024
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Treating visual impairment to improve dementia status
You've successfully added Cornea/External Disease in Optometry to your alerts. You will receive an email when new content is published. Click Here to Manage Email Alerts We were unable to process your request. Please try again later. If you continue to have this issue please contact customerservice@slackinc.com. Large retrospective studies have demonstrated that visual impairment is a risk factor for developing cognitive impairment, including dementia.
VIDEO: Study data show efficacy of Miebo in range of patients with dry eye disease
You've successfully added Cornea/External Disease in Ophthalmology to your alerts. You will receive an email when new content is published. Click Here to Manage Email Alerts We were unable to process your request. Please try again later. If you continue to have this issue please contact customerservice@slackinc.com. In this Healio Video Perspective from the World Ophthalmology Congress,John D.
VIDEO: Short- and long-term data show favorable outcomes for Miebo
You've successfully added to your alerts. You will receive an email when new content is published. Click Here to Manage Email Alerts We were unable to process your request. Please try again later. If you continue to have this issue please contact customerservice@slackinc.com. In this Healio Video Perspective from the World Ophthalmology Congress,John D. Sheppard, MD, MMSc, FACS,of Virginia Eye Consultants discusses clinical trial data for Miebo for the treatment of dry eye disease.
Investigating and Mitigating the Performance-Fairness Tradeoff via Protected-Category Sampling
1. Introduction As machine learning (ML) algorithms increasingly dominate decision-making and decision-assistance systems, their widespread deployment across various sectors raises pressing issues about the fairness and transparency of their predictions [1]. The potential for these algorithms to perpetuate or exacerbate existing societal biases has propelled a significant body of research to investigate and mitigate algorithmic unfairness.
Creature Feature: Atlantic Sturgeon
Sturgeon are ancient fish dating back at least 70 million years (with fossil records as old as 120 million years). Two species can be found along the East Coast of North America from southern Canada to northern Florida: the Atlantic sturgeon (Acipenser oxyrinchus) and the shortnose sturgeon (A. brevirostrum).
VIDEO: Miebo shows efficacy for mild, moderate dry eye treatment
You've successfully added to your alerts. You will receive an email when new content is published. Click Here to Manage Email Alerts We were unable to process your request. Please try again later. If you continue to have this issue please contact customerservice@slackinc.com. SEATTLE — In this Healio Video Perspective from the ARVO meeting, John D. Sheppard, MD, MMSc, FACS,discusses a post hoc analysis investigating Miebo for the treatment of dry eye disease at different levels of severity.
VIDEO: Miebo improves dry eye signs, symptoms with ‘unprecedented’ safety
Read more You've successfully added Cornea/External Disease in Ophthalmology to your alerts. You will receive an email when new content is published. Click Here to Manage Email Alerts We were unable to process your request. Please try again later. If you continue to have this issue please contact customerservice@slackinc.com. In this Healio Video Perspective from the ASCRS meeting,John D.
[2403.10730] Counterfactual Analysis of Neural Networks Used to Create Fertilizer Management Zones
[Submitted on 15 Mar 2024] Title:Counterfactual Analysis of Neural Networks Used to Create Fertilizer Management Zones Download a PDF of the paper titled Counterfactual Analysis of Neural Networks Used to Create Fertilizer Management Zones, by Giorgio Morales and John Sheppard Download PDF HTML (experimental) Abstract:In Precision Agriculture, the utilization of management zones (MZs) that take into account within-field variability facilitates effective fertilizer management.
Tolerability of current treatments for dry eye disease
Back to Journals » Clinical Ophthalmology » Volume 18 Authors Gupta PK , Toyos R, Sheppard JD, Toyos M , Mah FS, Bird B, Theriot PE , Higgins D Received 21 February 2024 Accepted for publication 6 July 2024 Published 16 August 2024 Volume 2024:18 Pages 2283—2302 DOI https://doi.org/10.2147/OPTH.S465143 Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 3 Editor who approved publication: Dr Scott Fraser Preeya K Gupta,1,2 Rolando Toyos,3 John D Sheppard,4...
VIDEO: Check corneal sensation to find cases of occult herpetic disease
You've successfully added to your alerts. You will receive an email when new content is published. Click Here to Manage Email Alerts We were unable to process your request. Please try again later. If you continue to have this issue please contact customerservice@slackinc.com. WAILEA, Hawaii — In this Healio Video Perspective from Hawaiian Eye 2024, John D. Sheppard, MD, MMSc, FACS, discusses herpetic disease and the use of a new noncontact quantitative corneal esthesiometer.
VIDEO: Capsule retractors stabilize capsular bag during complex cataract surgery
Read more You've successfully added Ophthalmology: Cataract Surgery to your alerts. You will receive an email when new content is published. Click Here to Manage Email Alerts We were unable to process your request. Please try again later. If you continue to have this issue please contact customerservice@slackinc.com. WAILEA, Hawaii — In this Healio Video Perspective from Hawaiian Eye 2024, John D. Sheppard, MD, MMSc, FACS, discusses capsule retractors as a tool for complex cataract surgery cases.
VIDEO: Miebo provides new approach to dry eye disease
You've successfully added Ophthalmology: Cornea/External Disease to your alerts. You will receive an email when new content is published. Click Here to Manage Email Alerts We were unable to process your request. Please try again later. If you continue to have this issue please contact customerservice@slackinc.com. SAN FRANCISCO — In this Healio Video Perspective from the AAO meeting, John D. Sheppard, MD, MMSc, discusses Miebo for the treatment of dry eye disease.
Veterans Day [Image 4 of 4]
Maintenance window scheduled to begin at February 14th 2200 est. until 0400 est. February 15th (e.g. yourname@email.com) Remember me Forgot Password? 14 GREAT LAKES, Ill. (Nov. 10, 2023) Capt. Steve Yargosz, commanding officer, Naval Station Great Lakes, speaks during U.S. Rep. Brad Schneider's annual Veterans Day breakfast at the College of Lake County in Grayslake, Ill.
VIDEO: Vevye shows minimal side effect profile for treating DED symptoms
You've successfully added Ophthalmology: Cornea/External Disease to your alerts. You will receive an email when new content is published. Click Here to Manage Email Alerts We were unable to process your request. Please try again later. If you continue to have this issue please contact customerservice@slackinc.com. SAN FRANCISCO — In this Healio Video Perspective from the AAO meeting, John D. Sheppard, MD, MMSc,discusses the use of Vevye from Harrow to treat dry eye disease.
UH Photos [Image 12 of 14]
Maintenance window scheduled to begin at February 14th 2200 est. until 0400 est. February 15th (e.g. yourname@email.com) Remember me Forgot Password? 14 GREAT LAKES, Ill. (Nov. 2, 2023) File photo of unaccompanied housing at Naval Station Great Lakes.
Change of Command Ceremony at Naval Station Great Lakes: Yargosz relieves Williamson as Commanding Officer
GREAT LAKES, Ill. — Capt. Steve Yargosz relieved Capt. Jason Williamson as Commanding Officer of Naval Station Great Lakes during a change of command ceremony on the morning of Tuesday, Oct. 17. The ceremony took place aboard the installation at the Seamanship Trainer on the mainside of the installation. Rear Adm. Wesley McCall, Commander, Navy Region Mid-Atlantic, served as the guest speaker.
Awardee [Image 6 of 6]
14 GREAT LAKES, Ill. (Oct. 20, 2023) Petty Officer 3rd Class Roman Rangel, Security receives the Bluejacket of the Quarter award from Capt. Steve Yargosz, Naval Station Great Lakes commanding officer.
Change of Command Ceremony at Naval Station Great Lakes: Yargosz relieves Williamson as Commanding Officer
12 GREAT LAKES, Ill. – Capt. Steve Yargosz relieved Capt. Jason Williamson as Commanding Officer of Naval Station Great Lakes during a change of command ceremony on the morning of Tuesday, Oct. 17. The ceremony took place aboard the installation at the Seamanship Trainer on the mainside of the installation. Rear Adm. Wesley McCall, Commander, Navy Region Mid-Atlantic, served as the guest speaker.
12 GREAT LAKES, Il. (Oct. 13, 2023) Sailors onboard Naval Station Great Lakes joins Capt. Jason J. Williamson, NSGL's commanding officer, in cutting a cake in honor of the Navy's birthday. Opened in 1911, Naval Station Great Lakes (NSGL) is the Navy’s largest training installation and the home of the Navy’s only Boot Camp. Located on over 1600 acres overlooking Lake Michigan, the installation includes 1,153 buildings with 39 on the National Register of Historic Places.
A Risk-Based Approach to Prognostics and Health Management Combining Bayesian Networks and Continuous-Time Bayesian Networks
Abstract:Performing general prognostics and health management (PHM), especially in electronic systems, continues to present significant challenges. The low availability of failure...View more Metadata Abstract: Performing general prognostics and health management (PHM), especially in electronic systems, continues to present significant challenges.
Great Lakes Commands Commemorate Battle of Midway [Image 5 of 5]
GREAT LAKES, Ill. (June 7, 2023) Musician 3rd Class Sara Vega from Navy Band Great Lakes sings the National Anthem at the Battle of Midway commemoration at the National Museum of the American Sailor. Fought on the high seas of the Pacific 81 years ago, June 4-7, 1942, this battle altered the course of World War II in the Pacific and thereby shaped the outcome of world events.
Great Lakes Commands Commemorate Battle of Midway
Maintenance window scheduled to begin at February 14th 2200 est. until 0400 est. February 15th REGISTER LOGIN GREAT LAKES, Ill. – The National Museum of the American Sailor hosted a ceremony commemorating 81st anniversary of the Battle of Midway at the museum June 7. The keynote speaker for the event was Capt. Jason J. Williamson, NSGL commanding officer. Sailors around the world celebrated the United States’ landmark victory at the Battle of Midway since this past weekend.
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