John Wu
Taiwan
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Articles by John Wu
Japanese, Australian banks lead Asia-Pacific short interest in Q3 2026
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Non-line-of-sight terahertz communications enabled by reflection and transmission
Abstract Terahertz communication is expected to be a key technology for future wireless networks, offering ultra-high capacity, beyond the limits of conventional radio-frequency systems. To enable practical implementation, investigating non-line-of-sight terahertz links is essential, but this remains largely unexplored. This paper presents an experimental demonstration of a non-line-of-sight terahertz link at 146.8 GHz using common building materials.
RDMA: cost effective agent-driven rare disease mining from electronic health records
Abstract Rare diseases affect 1 in 10 Americans yet remain systematically underdocumented in clinical records. ICD-based systems cannot capture their breadth, over 50% of Orphanet codes lack a direct ICD mapping and only 2.2% of HPO codes have matching ICD codes, leaving patient populations invisible and delaying diagnosis.
The landscape for in vivo CAR T cell therapies
Chimeric antigen receptor (CAR)-T cell therapy is well-established for blood cancers, with promising early data for autoimmune diseases and solid tumours. By engineering a patient’s T cells to recognize disease-associated cell-surface proteins, CAR-T therapies induce immune-mediated clearance of pathological cells. Enjoying our latest content?
Chinese megabanks expected to grow net profits as margins stabilize
The net profits of China's state-owned megabanks are expected to grow in the first half of 2026 as net interest margins stabilize. Industrial and Commercial Bank of China Ltd. (ICBC), the world's largest lender by assets, is expected to post a 9.0% year-over-year growth in net income for the January-to-June period to 179.23 billion yuan ($26.66 billion), according to the average analyst estimate on Visible Alpha. The net profit of Agricultural Bank of China Ltd.
Literature Review of Fabricated Artifacts for X-ray Computed Tomography
This report provides a comprehensive literature review of fabricated artifacts, commonly referred to as phantoms, used for the performance evaluation of X-ray computed tomography (XCT) systems. As XCT is increasingly adopted for high-precision metrology in the industrial sectors, including semiconductor manufacturing, establishing confidence in measurement results through well-characterized references is essential.
Chinese, Indian banks lead Asia-Pacific peers in share price discounts
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ICLR 2026
Overview The International Conference on Learning Representations (ICLR) is the premier gathering of professionals dedicated to the advancement of the branch of artificial intelligence called representation learning, but generally referred to as deep learning.
Chinese megabanks' net interest margins poised for turnaround in 2026
These are technologies that help enhance functionality, improve your user experience, and tailor your use of our digital services. For example, functionality Cookies can be used to remember pages and products you have viewed in order to enhance and personalize your experience when you visit our digital services. These are technologies used for targeted advertising and marketing.
A modular LLM framework for explainable price outlier detection
Detecting product price outliers is important for retail and e-commerce stores as erroneous or unexpectedly high prices adversely affect competitiveness, revenue, and consumer trust. Classical techniques offer simple thresholds while ignoring the rich semantic relationships among product attributes. We propose an agentic Large Language Model (LLM) framework that treats outlier price flagging as a reasoning task grounded in related product detection and comparison.
Singapore banks count on noninterest incomes to offset margin headwinds
Large Singapore banks will likely count on boosting noninterest incomes as falling interest rates damp net interest margins (NIM). DBS Group Holdings Ltd. reported 10.3% year-over-year decline in net profit to S$2.26 billion during the October-to-December quarter of 2025, bringing NIM into focus. Rival Oversea-Chinese Banking Corp. Ltd. (OCBC) posted a 3.6% net profit increase from a year ago, but down 11.6% from the previous quarter. United Overseas Bank Ltd.
Hong Kong Exchange aims to strengthen position as leading global IPO destination
Hong Kong Exchanges and Clearing Ltd. expects its strong pipeline of initial public offerings to strengthen its position as a leading global destination for equity fund raising in 2026. The exchange hosted 119 IPOs in 2025, through which companies raised an aggregate HK$286.9 billion. This was driven by strong interest and increased participation of international and mainland Chinese investors.
Goodbye, scalpers: how blockchain can finally fix the broken ticketing industry Original
For decades, the ticketing industry has remained stubbornly opaque, inefficient, and riddled with middlemen. From exorbitant fees and rampant scalping to bot-driven resales and counterfeit tickets, fans and organizers alike have suffered under a system that prioritizes profits over experience. Blockchain technology offers a way out – a path to restore fairness, transparency, and direct engagement between fans and the artists or teams they love.
World's largest lender expects NIM decline to reach 'inflection point'
Industrial and Commercial Bank of China Ltd. expects its interest margin to reach an inflection point as interest rates stabilize. For the first three quarters of 2025, Industrial and Commercial Bank of China (ICBC) reported a year-over-year decrease of 0.7% in net interest income to 473 billion yuan, with net interest margin (NIM) at 1.28% ― down just 2 basis points from three months ago and 15 bps from a year ago, according to the lender's Oct. 30 results release.
Crypto and DeFi in 2026: Adoption, Innovation, and the Road Ahead
As crypto and DeFi continue to shed their outsider status, with regulatory clarity improving and integration with traditional systems deepening, the stage is being set for broader adoption of digital assets and innovations in how we think about ownership and identity. Having surpassed the halfway point of 2025, it’s clear that crypto and DeFi are no longer on the fringes of the financial system.
Comctx: A Better Cross-Context Communication Library Than Comlink
Comlink performs great for Web Worker communication, which is its main design goal. However, when you want to use it in other environments, you'll find the adaptation work extremely difficult. I developed Comctx to solve this problem. It maintains Comlink's simple API while making environment adaptation easy through an adapter pattern. What Problem Does It Solve Comlink is primarily designed for Web Worker.
Basicity–Controlled C–H Bond Activation by a Structurally Characterized Ni(III)–Hydroxo Complex
Introduction Click to copy section linkSection link copied! The selective oxidation of strong C–H bonds remains a fundamental challenge in synthetic chemistry, with broad implications for biological transformations and industrial processes. (1−3) Nickel(II) complexes have been extensively explored for alkane hydroxylation and olefin epoxidation using oxidants such as m–chloroperbenzoic acid (m–CPBA), hypochlorite, and hydrogen peroxide.
Basicity–Controlled C–H Bond Activation by a Structurally Characterized Ni(III)–Hydroxo Complex
Introduction Click to copy section linkSection link copied! The selective oxidation of strong C–H bonds remains a fundamental challenge in synthetic chemistry, with broad implications for biological transformations and industrial processes. (1−3) Nickel(II) complexes have been extensively explored for alkane hydroxylation and olefin epoxidation using oxidants such as m–chloroperbenzoic acid (m–CPBA), hypochlorite, and hydrogen peroxide.
The landscape for radioligand therapies in oncology
External beam radiotherapy (EBRT) is a cornerstone in cancer management. Radiation is lethal to cancer cells, but the exposure of neighbouring healthy tissues can lead to dose-limiting toxicity. The localized delivery of EBRT also limits its ability to treat disseminated disease.
Agentic AI and blockchain technology are a powerful combination
Now Polynomials above 4 degrees have a shiny new target on their back. Two mathematicians have used a new geometric approach in order to address a very old problem in algebra. In school, we often learn how to multiply out and factor polynomial equations like (x² – 1) or (x² + 2x + 1). In real life, …
Agentic AI and blockchain technology are a powerful combination
Throughout history there have been very few moments when two transformational technologies emerge in parallel — and it's even rarer that their paths converge in ways that amplify each other's strengths. This is exactly, however, what we're currently...
Navigating SMA Management Challenges for Hedge Fund Managers
Separately managed accounts (SMAs) are gaining increasing traction in the hedge fund industry. Nearly half of hedge fund managers now offer SMAs, with an additional 10% planning to implement them within the next 12 months. This growth is driven by regulatory pressures, investor demands for transparency and technological advancements. Larger funds, particularly those with assets under management (AUM) exceeding £10bn, are more likely to offer SMAs (Hedgeweek 2025 Investor Survey).
How open innovation technology is driving collaboration across borders
Open innovation has evolved with tokenization, enabling secure, global collaboration and knowledge-sharing across industries. Unlike centralized corporate structures, tokenomics fosters transparency, trust, and fair value distribution, empowering communities over corporations. Tokenization accelerates open innovation, reshaping business by leveraging shared technology, global talent, and decentralized incentives for sustainable, knowledge-driven growth.
Biopharma Trends: Focus on Innovation Amid Complexity
The companies that thrive will focus on their core areas to drive innovation and efficiency while accelerating speed and agility. Scientific understanding of the biological drivers of disease, combined with the ability to influence human biology, has never been greater.We expect new development to accelerate, delivering a wave of breakthrough drugs that will transform the treatment of diseases with significant unmet need.
Focusing on Innovation amid Complexity
The companies that thrive will focus on their core areas to drive innovation and efficiency while accelerating speed and agility. Scientific understanding of the biological drivers of disease, combined with the ability to influence human biology, has never been greater.We expect new development to accelerate, delivering a wave of breakthrough drugs that will transform the treatment of diseases with significant unmet need.
The targeted protein degradation landscape
FROM THE ANALYST'S COUCH 27 November 2024 Many human diseases are driven by abnormal protein expression. Yet, about 85% of proteins are considered ‘undruggable’ with conventional methods owing to factors such as elusive binding sites, non-enzymatic functions or large protein–protein interfaces. Targeted protein degradation (TPD) is a promising new approach poised to unlock these targets by repurposing endogenous protein disposal systems to remove disease-causing proteins.
Facing the Unique Operational Challenges of Multi-Strategy Portfolios
Looking back on 2023, it is evident it was a remarkable year for multi-strategy hedge funds, often referred to as “pod shops.” According to Bloomberg, industry giants Millennium Management and Citadel have returned 10% and 15% respectively in this space. On the back of this success, 2024 has seen the launch of several major multi-strategy launches with Bobby Jain’s Jain Global leading the pack initially aiming for a record-breaking launch of $8-10 billion (recently adjusted to $6-8 billion).
WebChat - Chat with anyone on any website.
#webdev #javascript #extensions #typescript This is an anonymous chat browser extension that is decentralized and serverless, utilizing WebRTC for end-to-end encrypted communication. It prioritizes privacy, with all data stored locally. The aim is to add chat room functionality to any website, you'll never feel alone again.
[2408.00657] Disentangling Dense Embeddings with Sparse Autoencoders
arXivLabs is a framework that allows collaborators to develop and share new arXiv features directly on our website. Both individuals and organizations that work with arXivLabs have embraced and accepted our values of openness, community, excellence, and user data privacy. arXiv is committed to these values and only works with partners that adhere to them. Have an idea for a project that will add value for arXiv's community? Learn more about arXivLabs.
China's Anhui Maanshan Rural Commercial Bank withdraws IPO application
Anhui Maanshan Rural Commercial Bank Co. Ltd. withdrew its application for an IPO, becoming the third mainland China lender to do so since the start of the year. Shenzhen Stock Exchange on July 2 terminated its review on the IPO of Anhui Maanshan Rural Commercial Bank after the bank withdrew its application, according to the website of the Chinese bourse. The bank became the third mainland lender, after Jiangsu Haian Rural Commercial Bank CO. LTD.
China's ICBC faces margin pressure in 2024 amid NIM decline
Industrial and Commercial Bank of China Ltd. (ICBC) flagged further pressure on margins in 2024 after a sharp drop in net interest margin (NIM) dragged on annual net profit at the world's biggest lender. ICBC on March 27 reported a year-over-year earnings growth of 0.8% to 363.99 billion yuan for 2023, with a 31 basis points (bps) contraction in its NIM to 1.61%. This contrasts with 2022, when the lender's net profit rose 3.5% even as NIM fell 19 bps over the previous year.
China's too-big-to-fail banks get breather on loss absorption capital
China's too-big-to-fail banks will need lower total loss absorption capital (TLAC) after the nation relaxed its rules to align with the Basel III framework, S&P Global Ratings said. New rules that came into effect this year reduced the risk-weighted assets output floor for the five global systemically important banks (G-SIBs) in China to 72.5%, the same as Basel III norms, from 80%. As a result, China's G-SIBs could lower their risk-weighted assets and, therefore, lower their TLAC needs.
Oncology Solutions
The rapid acceleration of oncology research and therapeutics presents a tremendous opportunity for life science companies, hospitals, and—most importantly—patients. BCG offers oncology consulting services to businesses, NGOs, and health care systems to help them uncover insights and create value. We partner with our clients to deliver end-to-end oncology solutions that span R&D and manufacturing to commercialization and customer engagement models.
China's latest rate cut likely to help prop up demand in property market
The People's Bank of China's latest cut to its benchmark mortgage interest rate could help prop up demand in the country's property market, according to experts. The Chinese central bank on Feb. 20 reduced its five-year Loan Prime Rate (LPR) to 3.95% from 4.20% and left the one-year LPR unchanged at 3.45%, according to a news release. It was the first reduction in the five-year LPR since May 2023.
Hong Kong details strategies to keep position as global financial hub
Hong Kong's securities and futures regulator said it will review how it positions the city to attract more fund raising activities and lean on technology and environmental, social and corporate governance (ESG) products to remain a world-class financial center. Boosting the competitiveness and appeal of its capital markets will be one of the key priorities of the Securities and Futures Commission (SFC) of Hong Kong, according to the regulator's three-year plan released on Jan. 23.
Chinese local finance vehicles face contagion risks over cross-default clauses
The recent near-default by a Chinese local government financing vehicle (LGFV) has underscored a potential contagion risk due to guarantees and cross obligations that are common in the sector, S&P Global Ratings said. A unit of Xi'an Qujiang Culture Holdings Co. Ltd. made a last-minute settlement of an overdue sum of 91.74 million yuan that was outstanding as of Dec. 26, 2023, Ratings said.
T+1 Settlement Cycle - From Pitfalls to Preparedness
Some people see the T+1 settlement cycle as a double-edged sword—while it brings substantive value to industry participants, such as higher liquidity, it exerts immense pressure on firms’ capabilities to successfully deliver manual trade delivery instructions to various market participants. For buy-side firms in the APAC region, time-zone differences will leave your middle and back office with a compressed timeframe for post-trade processing.
Builders, the bear market is almost over
After 2022’s market crash and the implosion of several notable blockchain companies, this has been a year of doubling down on projects of substance. Web3 has taken 2023 as its year of reflection and constitution. That said, I firmly believe that 2024 will see builders’ hard work and grit pay off — next year, the public will see the fruits of our bear market labor.
Global money managers seek investment opportunities in era of higher rates
A "new normal" of high global interest rates, elevated Treasury yields and cash sitting on the sidelines are among the key concerns for some of the world's top money managers speaking at an event in Hong Kong on Nov. 8. Global central banks, led by the US Federal Reserve, have pushed interest rates higher since early 2022 to tamp inflationary pressures. Most economists predict rates will stay elevated for longer.
Global money managers seek investment opportunities in an era of higher rates
A "new normal" of high global interest rates, elevated Treasurys yields and cash sitting on the sidelines are among the key concerns for some of the world's top money managers speaking at an event in Hong Kong on Nov. 8. Global central banks, led by the US Federal Reserve, have pushed interest rates higher since early 2022 to tamp inflationary pressures. Most economists predict rates to stay elevated for longer.
China central bank not worried about risks from property, local governments
China central bank not worried about risks from property, local governments China's central bank is not overly worried about systemic risks from a downturn in the nation's property sector and high local government debt, a senior executive said in Hong Kong on Nov. 7.
Chinese Banks grapple with problem loans amid economic difficulties Original
Problem loans are in the spotlight at major Chinese banks, as asset quality takes a knock from multiple factors, including geopolitical tensions, slow post-pandemic recovery and an ailing real estate sector. Aggregate Stage 2 loans, which measure loans that carry a higher credit risk under International Financial Reporting Standards (IFRS 9) accounting standards, increased year over year in the January-to-June periodat large Chinese banks, S&P Global Market Intelligence data shows.
China regional banks could take 2.2 trillion yuan hit from local government arms
China's regional banks could face a 2.2 trillion yuan hit in capital losses in the next few years due to debt restructuring at local government finance arms, according to an S&P Global Ratings estimate. In a worst-case scenario, 74% of the regional banks' lending to local government financing vehicles (LGFV) in China could require debt restructuring, according to a sensitivity analysis the rating agency published Oct. 19.
T+1 Settlement Cycle and Its Global Impacts
The Securities Exchange Commission (SEC) is set to shorten the settlement cycle for US securities markets next spring from T+2 to T+1. In the international context, any party trading in the US—irrespective of domicile—and transacting in relevant instruments will be impacted by the change.
China's new loans decline in September as growth outlook stays tepid
New bank loans in China declined 6.5% year over year in September after a surge in August, reflecting the multiple challenges facing the world's second-biggest economy. Chinese banks extended 2.31 trillion yuan of new domestic currency loans in September, compared with 2.47 trillion yuan in the same month a year earlier,according to data released by the People's Bank of China on Oct. 13.
Video Startup 'Captions' Unveils New AI Dubbing App 'Lipdub' with Gen Z Slang
Venture into the world of AI-driven video dubbing with a touch of Gen Z flair. Captions, a budding AI video startup, has been making waves in the tech industry. Founded by Gaurav Misra, an ex-design engineering head at Snap and a former software development engineer at Microsoft, the startup is on a mission to revolutionize video dubbing. The company recently secured a whopping $25 million in funding from leading venture capitalists. But that's not all.
BioNetGMMFit: estimating parameters of a BioNetGen model from time-stamped snapshots of single cells - npj Systems Biology and Applications
Abstract Mechanistic models are commonly employed to describe signaling and gene regulatory kinetics in single cells and cell populations. Recent advances in single-cell technologies have produced multidimensional datasets where snapshots of copy numbers (or abundances) of a large number of proteins and mRNA are measured across time in single cells.
New loans in China rebound in August as authorities step up economic support
New bank loans in China rebounded in August in an indication that credit supply will be kept steady to support the world's second-biggest economy. In a reverse of July's slump, banks in China extended an aggregate 1.36 trillion yuan of new domestic currency loans in August, a nearly three-fold increase from the previous month's 346 billion yuan, according to data released by the People's Bank of China (PBOC) on Sept. 11. Measured over the previous year, new yuan loans rose 8.8%.
The next-generation CAR-T therapy landscape
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