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Jolene Caifeng Ho on Muck Rack

Jolene Caifeng Ho

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Articles

A practical and accessible workflow for bulk TCR sequencing from buffy coat samples without T cell enrichment

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By Ah-Jung Jeon, Jolene Caifeng Ho, Ming Xue Wee, Seng Chong Teo, Suit-Fong Chan
| Nature Verified
Abstract T cell receptor (TCR) sequencing enables high-resolution characterization of the adaptive immune repertoire and is increasingly applied in clinical research and disease monitoring. However, many existing workflows rely on fresh peripheral blood mononuclear cells (PBMCs), highly purified T cell populations, or specialized equipment such as cell sorters, limiting their accessibility in routine laboratory settings and biobank-derived samples.
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