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Jonathan Graae

As seen in: Nature, Wiley Online Library, Cell Reports
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Articles by Jonathan Graae

Red Blood Cell Surface Proteins and Cryopreservation for Tracking Altered Erythropoiesis

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By Martin Thomassen, Thomas Bonne, Jonathan Graae
| Wiley Online Library Verified
1 Introduction Manipulation of red blood cell or plasma volume is prohibited in competitive sports but has historically been used by some to artificially enhance performance. A particularly potent method for manipulating blood volume is recombinant human erythropoietin (rhEpo), which increases total hemoglobin mass and enhances performance, even at micro doses [1]. Direct detection of rhEpo in blood or urine is highly sensitive with up to ~90% sensitivity 72 h post-microdosing [2].
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Genetic and training adaptations in the Haenyeo divers of Jeju, Korea

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By Diana Aguilar-Gómez, Jacob Bejder, Jonathan Graae, Yelin Ko, Andrew Vaughn, Kendell Clement, Martin Tristani-Firouzi, Joo-Young Lee, Nikolai B. Nordsborg, Rasmus Nielsen, Melissa A. Ilardo
| Cell Reports Verified
Keywords evolutionary adaptation natural selection cardiovascular physiology breath-hold diving Research topic(s) CP: Genomics Introduction Extraordinary human populations have inhabited nearly every environment on the planet, adopting unique lifestyles and strategies to survive. The extreme conditions faced by these populations have imposed natural selection, introducing heritable adaptive variation.
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Genetic and training adaptations in the Haenyeo divers of Jeju, Korea

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By Diana Aguilar-Gómez, Jacob Bejder, Jonathan Graae, Yelin Ko, Andrew Vaughn, Kendell Clement, Martin Tristani-Firouzi, Joo-Young Lee, Nikolai B. Nordsborg, Rasmus Nielsen, Melissa A. Ilardo
| Cell Reports Verified
Keywords evolutionary adaptation natural selection cardiovascular physiology breath-hold diving Research topic(s) CP: Genomics Introduction Extraordinary human populations have inhabited nearly every environment on the planet, adopting unique lifestyles and strategies to survive. The extreme conditions faced by these populations have imposed natural selection, introducing heritable adaptive variation.
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Time-course of muscle fatigue development during intense exercise in hypoxia and normoxia - Scientific Reports

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By Jacob Bejder, Ricardo Barbieri, Eduardo Campos, Jens Bangsbo, Lars Nybo, Jonathan Graae
| Nature Verified
Abstract This study is the first to determine how hypoxia affects human muscle fatigue kinetics and metabolic perturbations during intense dynamic exercise. Using randomized, single-blinded crossover designs, three trials of two-legged knee extensions were performed under hypoxic (HYP, FiO₂ 0.135) and normoxic (NOR) conditions. Trial 1 (n = 8): quadriceps femoris twitch force (Ftw) was measured before, during, and after 4 min intense exercise followed by exhaustive exercise.
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