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Jonathan M. Barasch on Muck Rack

Jonathan M. Barasch

As seen in: Nature, The Lancet, Pediatrics
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Articles

Epithelial cell states associated with kidney and allograft injury - Nature Reviews Nephrology

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By Christian Hinze, Svjetlana Lovric, Philip F. Halloran, Jonathan M. Barasch
| Nature Verified
Abstract The kidney epithelium, with its intricate arrangement of highly specialized cell types, constitutes the functional core of the organ. Loss of kidney epithelium is linked to the loss of functional nephrons and a subsequent decline in kidney function. In kidney transplantation, epithelial injury signatures observed during post-transplantation surveillance are strong predictors of adverse kidney allograft outcomes.
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Molecular nephrology: types of acute tubular injury

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By Katherine Xu, Miriam Callahan, Jonathan M. Barasch, Prasad Devarajan
| Nature Verified
Abstract The acute loss of kidney function has been diagnosed for many decades using the serum concentration of creatinine — a muscle metabolite that is an insensitive and non-specific marker of kidney function, but is now used for the very definition of acute kidney injury (AKI). Fortunately, myriad new tools have now been developed to better understand the relationship between acute tubular injury and elevation in serum creatinine (SCr).
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The definition of acute kidney injury - Authors' reply

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By Jonathan M. Barasch, Joseph Bonventre, Richard Zager
| The Lancet Verified
We thank John A Kellum and Norbert Lameire for their letter in response to our Comment.1x1Barasch, J, Zager, R, and Bonventre, JV. Acute kidney injury: a problem of definition. Lancet.
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