Jonaz Ripswedan on Muck Rack

Jonaz Ripswedan

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Phenylacetylglutamine and trimethylamine N‐oxide: Two uremic players, different actions

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By Sam Hobson, ABDUL RASHID QURESHI, Jonaz Ripswedan, Lars Wennberg
| Wiley Online Library Verified
Abstract Background Chronic kidney disease (CKD) patients exhibit a heightened cardiovascular (CV) risk which may be partially explained by increased medial vascular calcification. Although gut-derived uremic toxin trimethylamine N-oxide (TMAO) is associated with calcium-phosphate deposition, studies investigating phenylacetylglutamine's (PAG) pro-calcifying potential are missing.
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