Jonnell Candice Small on Muck Rack

Jonnell Candice Small

As seen in: Nature, Cell Chemical Biology
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Articles

Subtype-selective prenylated isoflavonoids disrupt regulatory drivers of MYCN-amplified cancers

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By Michael Stokes, Alessandro Vasciaveo, Jonnell Candice Small, Jacob D. Daniels
| Cell Chemical Biology Verified
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Mesenchymal subtype neuroblastomas are addicted to TGF-βR2/HMGCR-driven protein geranylgeranylation

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By Michael Stokes, Kenichi Shimada, Jonnell Candice Small, Alessandro Vasciaveo
| Nature Verified
Abstract The identification of targeted agents with high therapeutic index is a major challenge for cancer drug discovery. We found that screening chemical libraries across neuroblastoma (NBL) tumor subtypes for selectively-lethal compounds revealed metabolic dependencies that defined each subtype.
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