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Jörg Kobarg

As seen in: Frontiers, MDPI
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Articles

The Mitochondrial Connection: The Nek Kinases’ New Functional Axis in Mitochondrial Homeostasis

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By Jörg Kobarg, Fernanda L. Basei, Camila C. Ferezin, Luidy K. Issayama
| MDPI
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
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Lestaurtinib inhibits Citron kinase activity and medulloblastoma growth through induction of DNA damage, apoptosis and cytokinesis failure

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By Di Cunto, Francesca Megiorni, Jörg Kobarg, Soma Sengupta
| Frontiers
1 Introduction Medulloblastoma (MB) is the most common malignant pediatric brain tumor (1, 2) and has been traditionally classified into four biological subgroups: WNT, Sonic Hedgehog (SHH), Group 3 and Group 4 (3–6). Due to the overlap between Group 3 and Group 4, it has recently been re-classified in: WNT-activated, SHH-activated and TP53-wildtype, SHH-activated and TP53-mutant, non-WNT/non-SHH (7).
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Use of a special Brazilian red-light emitting railroad worm Luciferase in bioassays of NEK7 protein Kinase and Creatine Kinase

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By Arina Perez, Bruno Aquino, Vadim Viviani, Jörg Kobarg
| Biomed Central (BMC)
Luciferases from bioluminescent organisms have many applications in biomedical areas, ranging from bioengineering, biosensors, cell biology to competition assays for bioassay development. One of the most important sources of luciferases are the bioluminescent beetles belonging to the Elateroidea superfamily, within Lampyridae (fireflies), Phengodidae (railroadworms) and Elateridae (click-beetles) [1, 2].
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