Jose Barrabés

The routine invasive strategy—systematic performance of early coronary angiography and, if feasible, revascularization—is a pillar of the management of patients with non-ST elevation acute coronary syndromes (NSTEACS) because it reduces the rates of cardiovascular death or myocardial infarction (MI) and the need for urgent revascularization.1 However, its benefits in older patients, especially those with frailty or comorbidities, have been questioned because these patients were...

References 1. Moya A, Sutton R, Ammirati F, Blanc JJ, Brignole M, Dahm JB, Deharo JC, Gajek J, Gjesdal K, Krahn A, Massin M, Pepi M, Pezawas T, Ruiz-Granell R, Sarasin F, Ungar A, van Dijk JG, Walma EP, Wieling W. Guidelines for the diagnosis and management of syncope (version 2009). Eur Heart J 2009;30:2631–71.Find this resource: Google Preview WorldCat Medline Web of Science 2.

Highlights • In patients with STEMI treated with primary percutaneous coronary intervention, iron deficiency is associated with larger infarcts, more extensive microvascular obstruction, and a higher frequency of adverse left ventricular remodeling. • An iron-deficient diet reduces the tolerance to ischemia/reperfusion in mice at least in part by interfering with the cardioprotective pathway eNOS/soluble guanylate cyclase/protein kinase G.