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Josée Frappier on Muck Rack

Josée Frappier

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Articles

CDK5RAP2 gene and tau pathophysiology in late-onset sporadic Alzheimer's disease

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By Justin Miron, Cynthia Picard, Nathalie Nilsson, Josée Frappier
| Alzheimer's & Dementia Verified
In AD subjects from the QFP cohort, CDK5RAP2 exhibits a significantly higher gene expression in the frontal cortex, the temporal cortex, and the cerebellum, as well as higher temporal cortical protein levels (Fig. 3Fig. 3). Microarray data from Hokama et al. [37][37] revealed a similar increase in CDK5RAP2 mRNA levels in both the frontal and temporal cortices of pathologically confirmed AD cases (data not shown).
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