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Joseph Loftus on Muck Rack

Joseph Loftus

Verified
  • Senior Social Editor, JOE.ie
  • Senior Social Editor, JOE
United Kingdom
As seen in: JOE, JOE.ie, The New York Times, Nature, Flipboard, UNILAD, 22 Words, Her.ie, The London Economic, Sports JOE, HerFamily, Mancunian Matters and
Editor @JOE_co_uk @Joedotie
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Articles

TWEAK/FN14 inhibition synergizes with oncogene-directed tyrosine kinase inhibitors to overcome resistance across multiple driver contexts

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By Glen Weiss, Joseph Loftus Verified, David W. Mallery, Nhan L. Tran
| Nature Verified
Abstract Oncogene-directed tyrosine kinase inhibitors (TKIs) have transformed the treatment of molecularly defined cancers; however, durable responses are frequently undermined by therapy-induced adaptive resistance. Beyond secondary kinase mutations, accumulating evidence suggests that stress-responsive, non-genetic survival pathways play a central role in attenuating TKI efficacy across oncogenic contexts.
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Update issued on Irish school closures as temperatures set to hit 30 degrees

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By Joseph Loftus Verified
| HerFamily Verified
It's the hottest May in decades. It's the question many of us asked ourselves as kids: just how hot does it have to get before we're sent home from school early? The short answer is that there is no official legal maximum temperature that automatically triggers school closures in Ireland. However, should temperatures climb above 30°C across several consecutive days and Met Éireann issue a Status Red warning, schools would be required to shut their doors.
Open in Who Shared Issue with article?

Update issued on Irish school closures as temperatures set to hit 30 degrees

|
By Joseph Loftus Verified
| Her.ie Verified
It's the hottest May in decades. It's the question many of us asked ourselves as kids: just how hot does it have to get before we're sent home from school early? The short answer is that there is no official legal maximum temperature that automatically triggers school closures in Ireland. However, should temperatures climb above 30°C across several consecutive days and Met Éireann issue a Status Red warning, schools would be required to shut their doors.
Open in Who Shared Issue with article?
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