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Articles by Joses Ho
Getting over ANOVA: estimation graphics for multi-group comparisons
Generations of statisticians have voiced concern about null-hypothesis significance testing for reducing research decision-making to dichotomous thinking, distancing researchers from the critical task of effect quantification1,2,3. As an alternative, estimation statistics focuses on effect size estimation, confidence intervals, data graphics and meta-analysis1,4.
Dopamine neurons that inform Drosophila olfactory memory have distinct, acute functions driving attraction and aversion
Loading metrics Open Access Peer-reviewed Research Article ? This is an uncorrected proof. Citation: Mohammad F, Mai Y, Ho J, Zhang X, Ott S, Stewart JC, et al. (2024) Dopamine neurons that inform Drosophila olfactory memory have distinct, acute functions driving attraction and aversion. PLoS Biol 22(11): e3002843.
Dopamine neurons that inform Drosophila olfactory memory have distinct, acute functions driving attraction and aversion
Abstract The brain must guide immediate responses to beneficial and harmful stimuli while simultaneously writing memories for future reference. While both immediate actions and reinforcement learning are instructed by dopamine, how dopaminergic systems maintain coherence between these two reward functions is unknown.
Global disparities in SARS-CoV-2 genomic surveillance - Nature Communications
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Abstract Genomic sequencing is essential to track the evolution and spread of SARS-CoV-2, optimize molecular tests, treatments, vaccines, and guide public health responses. To investigate the global SARS-CoV-2 genomic surveillance, we used sequences shared via GISAID to estimate the impact of sequencing intensity and turnaround times on variant detection in 189 countries.
By Anderson F. Brito, Elizaveta Semenova, Gytis Dudas, Joses Ho, George Githinji, Charles N. Agoti, Lucy E. Matkin, Charles A. Whittaker, Benjamin P. Howden, Vitali Sintchenko, Tulio de Oliveira, Paola Cristina Resende, Fernando Spilki, Renato Santana Aguiar, Maria Van Kerkhove, Oliver G. Pybus, Seth Flaxman, Marc A. Suchard, Guy Baele
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Moving beyond P values: data analysis with estimation graphics
Fig. 1: The evolution of two-group data graphics. Data availability The Matlab, Python and R packages are available on GitHub (https://github.com/ACCLAB/DABEST-python) and are licensed under the BSD 3-Clause Clear License. References 1. Berkson, J. J. Am. Stat. Assoc. 37, 325–335 (1942). Article Google Scholar 2. Benjamin, D. J. et al. Nat. Hum. Behav. 2, 6–10 (2017). Article Google Scholar 3. Cohen, J. Am. Psychol. 49, 997–1003 (1994). Article Google Scholar 4. Cumming, G. & Calin-Jageman, R.
The Integrator Complex Prevents Dedifferentiation of Intermediate Neural Progenitors back into Neural Stem Cells
Highlights • Drosophila Integrator complex is important for larval brain development • Neural-progenitor-specific depletion of integrator induces ectopic type II neuroblasts • DamID analysis identifies earmuff as an IntS5-binding site in INPs • Integrator promotes the expression of erm and brm in type II neuroblast lineages Summary Mutations of the Integrator subunits are associated with neurodevelopmental disorders and cancers. However, their role during neural development is poorly understood.
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