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Articles by Ju Lu
5-HT 2A receptors in layer 5 pyramidal neurons mediate the neuroplastic but not the hallucinogenic effects of psilocybin
Abstract It is unclear how serotonin 2A receptors (5-HT2ARs) in cortical layer 5 pyramidal neurons differentially contribute to psilocybin-induced hallucinations versus neuroplasticity. Here we show that psilocybin promotes synapse formation and maturation while accelerating the elimination of pre-existing synapses.
Connectomic evidence that ordered activity drives neuromuscular network formation
Abstract We reconstructed complete connectomes between motor neurons and muscle fibers in small mouse muscles from birth through successive stages of postnatal development, when synaptic reorganization is most prominent.
Postoperative recurrence patterns and prognostic determinants in early-onset early-stage gastric cancer: A multicenter retrospective real-world study
Keywords Gastric cancer Early-stage Early-onset Postoperative recurrence Prognosis Get full text access Log in, subscribe or purchase for full access. REFERENCES 1. Wang, X. ∙ Gao, X. ∙ Yu, J. ... Emerging trends in early-onset gastric cancer Chin Med J (Engl). 2024; 137:2146-2156 [PubMed: 39148190] 2. GBD 2019 Adolescent Young Adult Cancer Collaborators The global burden of adolescent and young adult cancer in 2019: a systematic analysis for the Global Burden of Disease Study 2019 Lancet Oncol.
Quantitative Analysis of the O‐RADS Classification Using Ultrasound Scoring Method (USM) and Its Application Significance
Conflicts of Interest The authors declare no conflicts of interest. References , , , and . 1990. “Doppler Ultrasound Color Flow Imaging in the Study of Breast Cancer: Preliminary Findings.” Ultrasound in Medicine & Biology 16, no. 6: 553–559. , , , , and . 2011. “GI-RADS Reporting System for Ultrasound Evaluation of Adnexal Masses in Clinical Practice: A Prospective Multicenter Study.” Ultrasound in Obstetrics & Gynecology 38, no. 4: 450–455. , , , et al. 2020.
Effects of Ti4+ Doping on the Structural Stability and Electrochemical Performance of Layered P2-Na0.7MnO2.05 Cathodes for Sodium-Ion Batteries
Open AccessArticle by Kexin Zheng 1,2, Jiawei Wang / 制备高端锰材料，室温湿法还原 二氧化锰矿 - [...] 王佳伟博士是贵州省贵阳市贵州大学材料与冶金学院的教授，本科生教学，硕士研究生导师，博士研究生导师 贵州大学冶金工程学.他还是专家委员会的成员 中国有色金属行业技术创新战略 贵州省厅专家库中的专家联盟 科学技术委员会专家 全国污染源普查员 贵州省 贵阳市生态局.他获得了有色金属专业的博士学位 中南大学冶金学（2008 年）。他为 《中国大百科全书》环境科学卷第三版。 主要从事高硫铝土矿脱硫研究 电解锰的技术、节能降耗 / 制备高端锰材料，室温湿法还原 二氧化锰矿 - 电解锰负极的资源化利用 炉渣， 湿矿渣（赤泥、锰渣、磷石膏）的无害性研究， 一种非燃烧多组分建筑材料的制备及其 在公路工程中的应用。 1,2, Haifeng Wang 1,2,*, Zhengqing Pei 1,2, Qian Wang 1,2, Xinjie Zhou 1,2, Dehua Ma 1,2 and Ju Lu 1,2 1 School...
State-dependent modulation of positive and negative affective valences by a parabrachial nucleus-to-ventral tegmental area pathway in mice
Introduction The state-dependent regulation of adaptive behavior is critical for animal survival. Sensory information such as pain and taste signals arising from peripheral tissues is transmitted to the lateral parabrachial nucleus (LPB) in the pons directly via the dorsal horn of the spinal cord and indirectly via the nucleus of the solitary tract (NTS) through the vagal ganglia (Chiang et al., 2020; Tan et al., 2020).
The flow of axonal information among hippocampal sub-regions 2: patterned stimulation sharpens routing of information transmission
Introduction The function of the trisynaptic loop in the mammalian hippocampus is widely understood to govern the processes of learning and episodic memory. However, the spike dynamics that support the specific functions of each sub-region of this network have not been compared in a unitary system. The trisynaptic loop is composed of distinct sub-regions that each have a unique computational role in integrating and processing information transmitted from the neocortex to the hippocampus.
Profiling neurotransmitter-evoked glial responses by RNA-sequencing analysis
Introduction Neurons and glia are the two major cell types in the central nervous system (CNS). Whereas neurons are the major mediators for all aspects of brain function, glia, although abundantly seen, are usually considered passive bystanders that provide nutrient and support (Allen and Lyons, 2018; Kim et al., 2020; Perez-Catalan et al., 2021).
An analog of psychedelics restores functional neural circuits disrupted by unpredictable stress
Abstract Psychological stress affects a wide spectrum of brain functions and poses risks for many mental disorders. However, effective therapeutics to alleviate or revert its deleterious effects are lacking. A recently synthesized psychedelic analog tabernanthalog (TBG) has demonstrated anti-addictive and antidepressant potential. Whether TBG can rescue stress-induced affective, sensory, and cognitive deficits, and how it may achieve such effects by modulating neural circuits, remain unknown.
Long-Term Consolidation of Ensemble Neural Plasticity Patterns in Hippocampal Area CA1
(A) To track E-SARE activation in CA1 pyramidal cells, we injected a virus from which E-SARE drove dVenus expression and the ePGK housekeeping promoter drove TurboFP635 expression. (B) Timeline of sessions for group 1 (four mice, 12–14 weeks old, 461 ± 103 [SD] cells per mouse, range 344–557557 cells, 1,845 cells total). (C) CA1 neurons’ green/red emission ratios for group 1 mice, relative to each cell’s mean ratio over days 1–3 of imaging (dashed line).
A Local Rebalancing Act Leads to Global Benefit
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Facile detection of tumor derived exosomes using magnetic nanobeads and SERS nanoprobes
Exosomes play an important role in intercellular communications. Here, we present a surface enhanced Raman scattering (SERS) based detection method for tumor derived exosomes using SERS nanoprobes and magnetic nanobeads. The SERS nanoprobe has a core-shell structure, with gold core-silver shell nanorods (Au@Ag NRs) as the SERS active core, Raman molecules as the SERS reporter and a silica layer as the protecting shell.
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