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7,4′‐dimethoxy‐3‐hydroxyflavone, a protease‐activated receptor 4 (PAR4) inhibitor with antioxidant activity, ameliorates diabetic endothelial dysfunction - Tsai - British Journal of Pharmacology - Wiley Online Library
CONFLICT OF INTEREST STATEMENT The authors declare no conflicts of interest. Supporting Information Filename Description bph70105-sup-0001-Supplementary_Legends.pdfPDF document, 741.7 KB Figure S1. Exploratory data: high glucose induces endothelial PAR4 expression independent of osmolarity. Human endothelial EA.hy926 cells were incubated with normal glucose (5.5 mM), high glucose (25 mM or osmotic control (5.5 mM D-glucose plus 19.5 mM D-mannitol) medium for 6 (a) or 48 (b) h.
Discovery of 5-Hydroxy-1,4-naphthoquinone (Juglone) Derivatives as Dual Effective Agents Targeting Platelet-Cancer Interplay through Protein Disulfide Isomerase Inhibition
Download Hi-Res ImageDownload to MS-PowerPointCite This:J. Med. Chem.
Discovery of 5-Hydroxy-1,4-naphthoquinone (Juglone) Derivatives as Dual Effective Agents Targeting Platelet-Cancer Interplay through Protein Disulfide Isomerase Inhibition
Download Hi-Res ImageDownload to MS-PowerPointCite This:J. Med. Chem.
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