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Jude Marvin Phillip on Muck Rack

Jude Marvin Phillip

As seen in: BioRxiv
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Articles

Single-cell morphology encodes functional subtypes of senescence in aging human dermal fibroblasts

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By Pratik Kamat, Chanhong Min, Jude Marvin Phillip, Nico Macaluso
| BioRxiv
Abstract Cellular senescence is an established driver of aging, exhibiting context-dependent phenotypes across multiple biological length-scales. Despite its mechanistic importance, profiling senescence within cell populations is challenging. This is in part due to the limitations of current biomarkers to robustly identify senescent cells across biological settings, and the heterogeneous, non-binary phenotypes exhibited by senescent cells.
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