Juihsuan Chou on Muck Rack

Juihsuan Chou

As seen in: BioRxiv, Texas Medical Center
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Articles

Development and Application of Analytical Methods for Genetic Interaction Mapping from Combinatorial CRISPR Screens in Human Cancer Cells

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By Juihsuan Chou
| Texas Medical Center
Dissertations and Theses (Open Access) Author ORCID Identifier 0000-0002-1685-5885 Date of Graduation 8-2026 Document Type Dissertation (PhD) Program Affiliation Quantitative Sciences Degree Name Doctor of Philosophy (PhD) Advisor/Committee Chair Traver Hart, Ph.D. Committee Member Swathi Arur, Ph.D. Committee Member Paul Scheet, Ph.D. Committee Member John Paul Y.C. Shen, M.D. Committee Member Han Xu, Ph.D. Abstract Development and Application of Analytical Methods for Genetic Interaction...
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"Z-Scores Outperform Similar Methods for Analyzing CRISPR Paralog Synth" by Juihsuan Chou, Nazanin Esmaeili Anvar et al.

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By Juihsuan Chou
| Texas Medical Center
Abstract Genetic screens offer a promising strategy for identifying tumor-specific therapeutic targets, but single-gene knockout screens often miss functionally redundant paralogs. Multiplex Cas9 and Cas12a CRISPR systems have been deployed to assay genetic interactions, but analysis pipelines vary considerably.
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The Updated Database of Pooled In Vitro CRISPR Knockout Li" by Lance C Novak, Juihsuan Chou et al.

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By Lance C. Novak, Juihsuan Chou, Medina Colic, Christopher Bristow
| Texas Medical Center
PICKLES (https://pickles.hart-lab.org) is an updated web interface to a freely available database of genome-scale CRISPR knockout fitness screens in human cell lines. Using a completely rewritten interface, researchers can explore gene knockout fitness phenotypes across cell lines and tissue types and compare fitness profiles with fitness, expression, or mutation profiles of other genes.
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