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Beyond Donor-Specific Antibodies: Molecular Characterization of Antibody-Mediated Rejection Using Tissue-Based Transcriptomics in Heart Transplantation
Abbreviations ABMR (molecular antibody-mediated rejection (MMDx)) AT1R (angiotensin II type 1 receptor) dd-cfDNA (donor-derived cell-free DNA) DSA (donor-specific antibody) EMB (endomyocardial biopsy) GEE (generalized estimating equation) HLA (human leukocyte antigen) IFN-γ (interferon gamma) IQR (interquartile range) ISHLT (International Society for Heart and Lung Transplantation) MFI (mean fluorescence intensity) MIC-A (MHC class I chain-related gene A) MMDx (Molecular Microscope Diagnostic...
A molecular reappraisal of quilty lesions: Insights from tissue and circulating biomarkers in heart transplantation
Abbreviations ABMR (molecular antibody-mediated rejection (MMDx)) ACR (acute cellular rejection) CAV (cardiac allograft vasculopathy) dd-cfDNA (donor-derived cell-free DNA) DSA (donor-specific antibody) EMB (endomyocardial biopsy) GEP (peripheral gene expression profiling) HR (hazard ratio) HT (heart transplantation) ISHLT (International Society for Heart and Lung Transplantation) MBF (myocardial blood flow) MBFR (myocardial blood flow reserve) MMDx (Molecular Microscope Diagnostic System)...
Enhanced Detection of Antibody-Mediated Rejection Using the Tissue-Based Molecular Microscope Diagnostic System (MMDx)
Abbreviations ABMR (molecular antibody-mediated rejection (MMDx)) AMR (antibody-mediated rejection (histology)) ACR (acute cellular rejection) AUC (area under the curve) dd-cfDNA (donor-derived cell-free DNA) DSA (anti-HLA donor-specific antibody) EMBx (endomyocardial biopsy) GEP (gene-expression profiling) HT (heart transplantation) LVEF (left ventricular ejection fraction) MFI (mean fluorescence intensity) MMDx (Molecular Microscope Diagnostic System) ROC (receiver operating curve) TTE...
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