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Julia M. Bartlett on Muck Rack

Julia M. Bartlett

As seen in: Color Research & Application, Nature, MDPI, Science Magazine, BioRxiv, The Eastern Echo, BCN Foodie Guide
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Articles

Differences in how NMDA antagonists modulate negative affective biases in male rats may serve as a predictor of clinical efficacy in major depressive disorder

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By Justyna K. Hinchcliffe, Katie Kamenish, Julia M. Bartlett, Roberto Arban, Bastian Hengerer, Emma Robinson
| Nature Verified
Abstract Affective biases shape cognitive and emotional behaviour and are important in major depressive disorder (MDD). Modulation of affective biases by the NMDA antagonist, ketamine, may underlie its antidepressant effects but not all NMDA antagonists are efficacious.
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Modulation of negative affective biases in male rats may predict the rapid and sustained antidepressant effects of different NMDA antagonists

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By Justyna K. Hinchcliffe, Katie Kamenish, Julia M. Bartlett, Roberto Arban
| BioRxiv
Abstract Affective biases influence cognitive and emotional behaviour and play a significant role in major depressive disorder. We have shown that the NMDA antagonist and rapid-acting antidepressant, ketamine, selectively modulates affective biases, a neuropsychological effect which may underlie its efficacy. Clinical studies with different NMDA antagonists have found mixed effects but the reasons for these differences in efficacy are not understood.
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Origami with Oatmeal!

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By Julia M. Bartlett
| The Eastern Echo Verified
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