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Julian Connor Eckel on Muck Rack

Julian Connor Eckel

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Cell atlas of the regenerating human liver after portal vein embolization - Nature Communications

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By Agnieska Brazovskaja, Philipp Wahle, Christiane Körner, Zhisong He, Michael Dannemann, Jochen Hampe, Daniel Seehofer, Theresa Schaffer, Julian Connor Eckel, René Hänsel, Georg Damm
| Nature Verified
Abstract The liver has the remarkable capacity to regenerate. In the clinic, regeneration is induced by portal vein embolization, which redirects portal blood flow, resulting in liver hypertrophy in locations with increased blood supply, and atrophy of embolized segments. Here, we apply single-cell and single-nucleus transcriptomics on healthy, hypertrophied, and atrophied patient-derived liver samples to explore cell states in the regenerating liver.
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