Juliet Chen

Abstract During development and tissue repair, cells reshape and reconfigure to ensure organs take specific shapes. This process is inherently three-dimensional (3D). Yet, in part due to limitations in imaging and data analysis, cell shape analysis within tissues have been studied as a two-dimensional (2D) approximation, e.g., the Drosophila wing disc. With recent advances in imaging and machine learning, there has been significant progress in our understanding of 3D cell and tissue shape in vivo.

Imagine that you are the only teammate online today in the Australian time zone in your company. You work in customer support and are trying to help multiple customers with questions that you’ve never come across before, and you can’t ask your teammates who won’t be online for at least another six hours.