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Articles by Jun Hyoung
Biosocial Determinants of Health Among Patients with Chronic Liver Disease and Liver Cancer
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EpCAM-targeted betulinic acid analogue nanotherapy improves therapeutic efficacy and induces anti-tumorigenic immune response in colorectal cancer tumor microenvironment | Journal of Biomedical Science | Full Text
Briefly, 5 mg of 2c and 50 mg of PLGA (75:25) were dissolved in 3 ml of organic solvent mixture [Dichloromethane (DCM): Acetone:: 4:1 v/v]. This solution was emulsified with 1.5 ml of 2.5% aqueous PVA by homogenizing at 20,000 rpm for 3 min using a high-speed homogenizer (IKA Laboratory Equipment, Model T10B, Ultra-Turrax, Staufen, Germany).
Metabolomic rewiring promotes endocrine therapy resistance in breast cancer
Approximately one-third of endocrine-treated women with estrogen receptor-alpha positive (ER+) breast cancers (BC) are at risk of recurrence due to intrinsic or acquired resistance. Thus, it is vital to understand the mechanisms underlying endocrine therapy resistance in ER+ BC to improve patient treatment. Mitochondrial fatty acid β-oxidation (FAO) has been shown to be a major metabolic pathway in triple-negative BC (TNBC) that can activate Src signaling.
Gut microbiota as a potential key to modulating humoral immunogenicity of new platform COVID-19 vaccines
Signal Transduction and Targeted Therapy, May 2023 This is a preview of a remote PDF: https://www.nature.com/articles/s41392-023-01445-0.pdf Seong, Hye, Choi, Bo Kyu, Han, Young-Hee, Kim, Jun Hyoung, Gim, Jeong-An, Lim, Sooyeon, Noh, Ji Yun, Cheong, Hee Jin, Kim, Woo Joo, Song, Joon Young. , Signal Transduction and Targeted Therapy, DOI: 10.1038/s41392-023-01445-0
Clinical implications of gut microbiota and cytokine responses in coronavirus disease prognosis
Hye Seong1, Jun H. Kim2, Young-Hee Han3, Ho S. Seo4, Hak J. Hyun1, Jin G. Yoon1, Eliel Nham1, Ji Y. Noh1, Hee J. Cheong1, Woo J. Kim1, Sooyeon Lim1* and Joon Y.
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