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Jun-liang Li

As seen in: Nature, PLOS ONE
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Articles

Fangchinoline restores TFEB-driven lysosomal biogenesis and blocks H1N1 infection

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By Fang Xie, Zhe Liu, Jun-liang Li, Ling-Dong Kong, Qi-Qi Li, Ke-Xin Ma, Fei Liu, Han Wang, Yao Wang, Xin Jia, Cui-qin Cheng, Yuan-yuan Qiao, Liang-dong Song
| Nature Verified
Abstract Influenza A viruses subvert lysosomal function to evade host degradation mechanisms. Using Connectivity Map (CMap) screening and transcriptomic analysis, we identified fangchinoline (Fan)—a bisbenzylisoquinoline alkaloid—as a potent enhancer of lysosomal gene expression. Owing to its alkaline properties, Fan accumulates within lysosomes, elevates luminal pH, and induces TFEB nuclear translocation, thereby restoring lysosomal biogenesis and initiating a TFEB-driven antiviral response.
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Correction: Research and application of digital measure management and control technology for characteristic low-efficiency gas wells in Gas Field A

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By Hao-Yang Li, Wen-hai Ma, Jun-liang Li, Pin-gang Ma
| PLOS ONE
The author Cheng-gang Jiang should not have been included in the author byline. The correct citation is: Li H-y, Ma W-h, Li J-l, Ma P-g, Yao D-s, Feng M-x, et al. (2025) Research and application of digital measure management and control technology for characteristic low-efficiency gas wells in Gas Field A. PLoS One 20 (5): e0323644. https://doi.org/10.1371/journal.pone.0323644. Reference 1. Li H-Y, Ma W-H, Li J-L, Jiang C-G, Ma P-G, Yao D-S, et al.
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Research and application of digital measure management and control technology for characteristic low-efficiency gas wells in Gas Field A

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By Hao-Yang Li, Wen-hai Ma, Cheng-gang Jiang, Jun-liang Li
| PLOS ONE
Loading metrics Open Access Peer-reviewed Research Article Citation: Li H-y, Ma W-h, Li J-l, Jiang C-g, Ma P-g, Yao D-s, et al. (2025) Research and application of digital measure management and control technology for characteristic low-efficiency gas wells in Gas Field A. PLoS One 20(5): e0323644.
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