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Articles by Jun Weng
ZnO Nanoparticles-Modified Unsaturated Polyester Resin Composites: Structural, Mechanical Properties and Surface Stability Under Sewage Sludge Exposure
Submitted: 23 September 2026 Posted: 24 September 2026 You are already at the latest version Unsaturated polyester resin (UPR) composites containing 0.02–1.00 %wt. ZnO nanoparticles (ZnO NPs) were prepared using an MEKP–cobalt octanoate curing system and evaluated for sanitary sewer components.
GPAM mediates mitochondrial dysfunction and the progression of alcoholic liver disease through lipid remodeling
Abstract INTRODUCTION RESULTS DISCUSSION MATERIALS AND METHODS Acknowledgments Supplementary Materials REFERENCES Information & Authors Metrics & Citations View Options References Figures Tables Media Share Abstract Lipid metabolic disorders and mitochondrial dysfunction are key and core pathological processes that contribute to the progression of alcoholic liver disease (ALD). However, the effects of lipid metabolism disorders on mitochondrial dysfunction in patients with ALD remain unknown.
Shikonin covalently binding to cysteine to inhibits the cleavage activity of the 3C-like serine main protease (Nsp4) of PRRSV-2 and suppresses viral replication in Marc-145 cells
Abstract Porcine reproductive and respiratory syndrome virus (PRRSV) remains a major economic threat to the global swine industry. The viral 3C-like serine main protease (non-structural protein 4, nsp4) is essential for replication and represents a promising drug target for antiviral intervention.
Design of minibinder proteins as universal antagonists against canine and human TNFα - Communications Biology
Abstract In this study, we resolve the complex structure of canine TNFα (cTNFα) trimer bound to nanobody molecules at a resolution of 3.1 Å using cryo-electron microscopy. Structural comparison between cTNFα and human TNFα (hTNFα) reveals that the non-conserved residue Phe83 in cTNFα induces a conformational change in a nearby loop, which significantly reduces the binding affinity of cTNFα to nanobody TNF30.
Insight Into the Mechanism of H+-Coupled Nucleobase Transport
Proceedings of the National Academy of Sciences of the United States of America 10.1073/pnas.2302799120 Post-print yes Animals, Biological Transport, Purines, Mutation, Binding Sites, Ascorbic Acid, Mammals, PurTCp, NAT gene family, H+-coupled transport, nucleobases, X-ray crystallography Weng, Jun; Zhou, Xiaoming; Wiriyasermkul, Pattama; et al., "Insight Into the Mechanism of H+-Coupled Nucleobase Transport" (2023). Faculty and Staff Publications. 3872.
Event #23: $1,500 Badugi | 2025 World Series of Poker
Event #23: $1,500 Badugi Event #17: $2,000 No-Limit Holdem Event #18: $10,000 Dealers Choice 6-Handed Championship Event #19: $500 COLOSSUS Event #20: $1,500 SHOOTOUT Event #21: $1,500 Pot-Limit Omaha Hi-Lo 8 or Better Event #22: $25,000 High Roller 6-Handed Event #23: $1,500 Badugi Event #24: $1,500 Pot-Limit Omaha Double Board Bomb Pot Event #25: $10,000 Seven Card Stud Championship Show All Events Top Chip Counts 9 266,000 7 minutes ago On the bubble at one of the tables, action was picked...
Puerarin alleviates atherosclerosis via the inhibition of Prevotella copri and its trimethylamine production
Z-HL, JW, JY and Y-HZ contributed equally. Contributors Z-HL, JW, JY and Y-HZ designed and supervised the study. JW, JY and Y-HZ collected and analysed the data. Q-YH, H-FS and Y-QH recruited subjects and collected samples. YD, Z-PW, Z-YW, G-HL, XL, R-HT and J-CD conducted animal, bacterial cultivation and mass spectrometry experiments. Z-HL wrote the manuscript. H-WZ and P-ZY contributed to text revision and discussion. ZL acts as guarantor of this study.
Lifestyle interventions in the management of systemic sclerosis: a systematic review of the literature
We aimed to investigate the efficacy of lifestyle interventions for the management of systemic sclerosis (SSc). We searched the databases Medline, Embase, Web of Science and Cinahl in June of 2021. We included studies conducted on five or more patients with SSc published between January 1st of 2000 and date of search, evaluating lifestyle interventions, excluding systematic reviews without meta-analyses.
Lifestyle interventions in the management of systemic sclerosis: a systematic review of the literature
SSc is a chronic connective tissue disease that primarily affects women, commonly in their fifth decade of life, and can manifest with limited cutaneous involvement, diffuse cutaneous involvement or with no cutaneous involvement [1]. The estimated prevalence ranges from 2 decades with varied study designs and a conservative approach in the CA of studies, treating unclearly fulfilled criteria as unfulfilled.
Facile fabrication of hypercrosslinked microporous polymer nanospheres for effective inhibition of triple negative breast cancer cells proliferation.
Treatment failure is one of the main lethal causes of human triple negative breast cancer (TNBC) patients due to inefficient drug administration. The present study demonstrated the development of functional microporous organic polymers (MOPs) as a potential drug carrier and its controlled release. Due to the existence of abundant pores and high surface area, MOPs have promoted the high drug payloads, facilitating prolonged retention time and improved drug release.
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