June-Bum Kim on Muck Rack

June-Bum Kim

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Articles

Anti-fibrotic effects of evogliptin in fibroblasts derived from post-burn hypertrophic scars

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By Youn Kyung Kee, Ya Zheng, Hui Cui, Yoon Cho, Yu ro, In Suk Kwak, Dong Hyun Kim, Cheong Hoon Seo, June-Bum Kim
| Nature Verified
Abstract Hypertrophic scar (HTS) frequently occurs after burn injury, characterized by persistent fibroblast activation, overexpression of α-smooth muscle actin (αSMA) and extracellular matrix (ECM) components. Complete scarless regeneration remains incompletely understood. Dipeptidyl peptidase-4 (DPP4) is a cell-surface serine protease, its inhibitors (DPP4i) have been associated with fibrosis. However, the functional role of evogliptin in HTS formation remains unclear.
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