Is this you? As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.
Claim your profile
Articles by Junpeng Qi
Chemically Programmable and Switchable CAR‐T Therapy
Research Article Dr. Junpeng Qi Corresponding Author E-mail address: jqi@scripps.edu Department of Immunology and Microbiology, The Scripps Research Institute, 130 Scripps Way, Jupiter, FL, 33458 USA Search for more papers by this author Dr. Kohei Tsuji Chemical Biology Laboratory, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Building 376 Boyles Street, Frederick, MD, 21702 USA Department of Medicinal Chemistry, Institute of Biomaterials and...
Affinity maturation, humanization, and co-crystallization of a rabbit anti-human ROR2 monoclonal antibody for therapeutic applications
Rebecca S. Goydel‡1, Justus Weber‡2, Haiyong Peng‡, Junpeng Qi‡, Jo Soden§, Jim Freeth§, HaJeung Park¶ and Christoph Rader‡3 ‡Department of Immunology and Microbiology, The Scripps Research Institute, Jupiter, Florida 33458 §Retrogenix Ltd., Chinley, High Peak SK23 6FJ, United Kingdom ¶X-Ray Crystallography Core, The Scripps Research Institute, Jupiter, Florida 33458 ↵3 To whom correspondence should be addressed: Dept.
Chemically programmable and switchable CAR‐T therapy
Research Article Christoph Rader Corresponding Author E-mail address: crader@scripps.edu The Scripps Research Institute, Department of Immunology and Microbiology, 130 Scripps Way, 33458 Jupiter, UNITED STATES Search for more papers by this author Abstract Although the cell surfaceome is predominantly targeted and drugged with antibodies, its pocketome fraction is only accessible to small molecules and constitutes a rich subset of binding sites with immense potential diagnostic and...
Affinity maturation, humanization, and co-crystallization of a rabbit anti-human ROR2 monoclonal antibody for therapeutic applications
Author contributions: R.S.G., J.W., J.S., J.F., and H. Park data curation; R.S.G., J.W., H. Peng, J.Q., J.S., J.F., H. Park, and C.R. formal analysis; R.S.G., J.W., H. Peng, J.S., J.F., H. Park, and C.R. investigation; R.S.G., J.S., J.F., and H. Park visualization; R.S.G., J.W., H. Peng, J.Q., J.S., J.F., and H. Park methodology; R.S.G., H. Park, and C.R. writing-original draft; R.S.G., J.W., H. Peng, J.Q., J.S., J.F., H. Park, and C.R. writing-review and editing; H. Peng, J.Q., and C.R. supervision; H.
Chemically Programmed Bispecific Antibodies in Diabody Format
Chemically programmed bispecific antibodies (biAbs) endow target cell-binding small molecules with the ability to recruit and activate effector cells of the immune system. Here we report a platform of chemically programmed biAbs aimed at redirecting cytotoxic T cells to eliminate cancer cells.
Chemically programmed bispecific antibodies in diabody format
Author contributions: C.R. conceived, designed, supervised, and analyzed experiments; E.W. conceived, designed, conducted, and analyzed biological syntheses, biochemical conjugations, and in vitro and in vivo experiments; T.R.B. Jr. conceived, designed, analyzed, and supervised chemical syntheses; C.G.N. conceived, designed, conducted, and analyzed chemical syntheses; J.Q. conducted and analyzed in vitro experiments; A.R.N. conducted and analyzed chemical syntheses and in vitro experiments;...
Targeting Stereotyped B Cell Receptors from Chronic Lymphocytic Leukemia Patients with Synthetic Antigen Surrogates
Chronic lymphocytic leukemia (CLL) is a disease in which a single B-cell clone proliferates relentlessly in peripheral lymphoid organs, bone marrow, and blood. DNA sequencing experiments have shown that about 30% of CLL patients have stereotyped antigen-specific B-cell receptors (BCRs) with a high level of sequence homology in the variable domains of the heavy and light chains.
Targeting Stereotyped B Cell Receptors from Chronic Lymphocytic Leukemia Patients with Synthetic Antigen Surrogates
Chronic lymphocytic leukemia (CLL) is a disease in which a single B-cell clone proliferates relentlessly in peripheral lymphoid organs, bone marrow, and blood. DNA sequencing experiments have shown that about 30% of CLL patients have stereotyped antigen-specific B-cell receptors (BCRs) with a high level of sequence homology in the variable domains of the heavy and light chains.
Show More
loading
Actions
Is this you?
As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.Get in touch with Junpeng
Contact Junpeng, search articles and posts on X, monitor coverage, and track replies from one place.
Learn more about Muck Rack