Citation: Laughlin M, Jack JT, Stephens SE, Bolin E, Millett PC, Jensen MO (2026) Experimental and computational models for intracardiac flow analysis with blood speckle imaging. PLoS One 21(5): e0349435. https://doi.org/10.1371/journal.pone.0349435 Editor: Muhammad Shakaib, NED University of Engineering and Technology, PAKISTAN Received: October 14, 2025; Accepted: April 30, 2026; Published: May 15, 2026 Copyright: © 2026 Laughlin et al.