Kaahini Jain

In a retrospective analysis of more than 12,000 adults who received multiple CBC tests across 20 years, the researchers showed that these reference intervals are far from widely generalizable. It’s known that people’s CBC ranges can shift due to factors such as genetics, disease history, and age. However, the new study suggests that individual patients have a set point — a stable value around which their CBC measures fluctuate.

Abstract Rationale: Opioid use during pregnancy can lead to negative infant health outcomes, including neonatal opioid withdrawal syndrome (NOWS). NOWS comprises gastrointestinal, autonomic nervous system, and neurological dysfunction that manifest during spontaneous withdrawal. Variability in NOWS severity necessitates a more individualized treatment approach.

Abstract Opioid use during pregnancy can lead to negative infant health outcomes, including neonatal opioid withdrawal syndrome(NOWS). NOWS comprises gastrointestinal, autonomic nervous system, and neurological dysfunction that manifest during spontaneous withdrawal. Current treatments involve non-pharmacological and pharmacological interventions, however, there is no one standardized approach, in part because of variability in NOWS severity.