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Articles

Effect of voxelotor on cerebral perfusion and cerebral oxygen metabolism and cardiac stress in adult patients with sickle cell disease

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By Kadère Konté, Liza Afzali-Hashemi, Anouk Schrantee, John Wood
| Wiley Online Library Verified
1 INTRODUCTION Sickle cell disease (SCD) is a hereditary hemoglobinopathy characterized by polymerization of the abnormal hemoglobin S (HbS), resulting in hemolytic anemia, a chronic inflammatory state, recurrent vaso-occlusive crises, and ischemic organ damage.1 One of the most devastating forms of organ damage is cerebral ischemia resulting in either stroke or silent cerebral infarcts (SCIs) due to episodes of acute and chronic ischemia.1 SCIs are asymptomatic small white matter lesions...
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Incidence of SARS‐COV‐2 infection in sickle cell patients presenting with a painful crisis: A 12‐month prospective cohort study

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By Kadère Konté, Erfan Nur, Man Tang, Jarom Heijmans
| Wiley Online Library Verified
LETTER TO THE EDITOR Kadère Konté, Corresponding Author k.konte@amsterdamumc.nl orcid.org/0000-0001-6637-0352 Department of Clinical Haematology, Amsterdam University Medical Centers, Amsterdam, The Netherlands Correspondence Kadère Konté, Department of Clinical Haematology, Amsterdam University Medical Centers, Meibergdreef 9, 1105AZ Amsterdam, The Netherlands.
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Systematic review with meta‐analysis: risk factors for thiopurine‐induced leukopenia in IBD - van Gennep - - Alimentary Pharmacology & Therapeutics - Wiley Online Library

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By Berrie Meijer, Martijn W. Heymans, Sara van Gennep, Kadère Konté
| Wiley Online Library Verified
Summary Background Thiopurine‐induced leukopenia, a frequently observed and potentially life‐threatening adverse event, complicates the clinical management of IBD patients. Aim To assess risk factors for thiopurine‐induced leukopenia in IBD. Methods MEDLINE, EMBASE, BIOSIS and Cochrane library were searched for studies reporting at least one risk factor for thiopurine‐induced leukopenia. Pooled odds ratio (OR) was calculated for each potential risk factor using a random effects model.
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