Kadidia P. Adula on Muck Rack

Kadidia P. Adula

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Articles

Synaptic vesicles transiently dock to refill release sites

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By Kristina Lippmann, Erik Jorgensen, Grant F. Kusick, Kadidia P. Adula
| Nature Verified
Abstract Synaptic vesicles fuse with the plasma membrane to release neurotransmitter following an action potential, after which new vesicles must ‘dock’ to refill vacated release sites. To capture synaptic vesicle exocytosis at cultured mouse hippocampal synapses, we induced single action potentials by electrical field stimulation, then subjected neurons to high-pressure freezing to examine their morphology by electron microscopy.
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