Kaisaierjiang Kadier

Abstract Coronary artery disease (CAD) remains a major contributor to morbidity and mortality worldwide. Heart sound analysis has been investigated as a noninvasive approach to CAD detection, although existing evidence has been inconsistent. This systematic review evaluated the diagnostic performance of heart sound analysis for identifying CAD (≥50% stenosis). A search of four databases identified 1082 records, among which 40 studies involving 13,814 participants met the inclusion criteria.

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Abstract Background The relationships of serum neurofilament light chain (NfL) levels with chronic kidney disease (CKD) and renal function indicators remain controversial, and comprehensive studies with large sample sizes are lacking. Methods In total, 2,051 participants aged 20 to 75 years were identified from the National Health and Nutrition Examination Survey (2013-2014 cycle).