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Kaitian Yin on Muck Rack

Kaitian Yin

As seen in: Nature
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Articles

Cortistatin antagonizes Piezo1-STING axis and facilitates mitochondrial homeostasis of keratinocytes by attenuating AGEs accumulation in diabetic ulcers

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By Guoli Ma, Yonggang Li, Ben Liu, Jingwei Bi, Mengfei Lv, Hang Li, Tengxiao Huang, Wenke Zhao, Chuanju Liu, Krasimir Vasilev, Xinyu Liu, Yunpeng Zhao, Zhijian Wei, Weiwei Li, Qinghao Yuan, Kaitian Yin, Gaoxin Jin
| Nature Verified
Abstract Diabetic complications frequently arise in mechanically stressed regions, yet the molecular links between biomechanical forces and metabolic dysfunction remain unclear. Here, we demonstrate that mechanical stress induces glucose accumulation and downstream metabolic stress in keratinocytes.
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