Kaitlin Williams

Abstract Hidradenitis Suppurativa (HS) is an inflammatory skin disorder with limited treatments and unclear etiology. While monogenic HS is linked to gamma secretase mutations, particularly in the NCSTN subunit, the pathogenesis of the more common sporadic form remains uncertain, though associated with risk factors such as diets high in ultra-processed foods. Consistent with the clinical overlap between sporadic and monogenic HS, we find loss of NCSTN protein in sporadic HS fibroblasts.

Abstract : Autoimmune (AI) diseases, which present in a multitude of systemic manifestations, have been connected to many underlying factors. These factors include the environment, genetics, individual microbiomes, and diet. An individual’s gut microbiota is an integral aspect of human functioning, as it is intimately integrated into the metabolic, mechanical, immunological, and neurologic pathways of the body. The microbiota dynamically changes throughout our lifetimes and is individually unique.

To search in site, type your keyword and hit enter Home / State / Governor Dunleavy Announces Cape... Additional Funds Will Expedite Completion of the Road to Arctic Port Site (FAIRBANKS, Alaska) – Governor Dunleavy announced from Kotzebue on Monday that funding will be secured to complete the road to Cape Blossom. The additional funding will expedite the completion of the road, which will link Kotzebue to a viable arctic port at Cape Blossom.