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Abstract Cardiovascular-kidney-metabolic (CKM) syndrome’s overall impact on major blinding eye diseases remains unclear. We included participants from the UK Biobank. Baseline CKM syndrome at study entry was classified into five stages according to the American Heart Association criteria. We calculated the absolute incidence rates of cataract, glaucoma, and age-related macular degeneration (AMD) across CKM stages.
Abstract The rising burden of endocrine and metabolic diseases demands scalable and accessible screening tools. Here we developed Reti-Pioneer, a multitask retinal imaging framework that integrates quality-aware modules with pre-trained foundation models for efficient, multidisease detection.
CONFLICT OF INTEREST STATEMENT The authors declare no conflicts of interest. DATA AVAILABILITY STATEMENT The UK Biobank data are available on application to the UK Biobank, and the analytic methods and study materials that support the findings of this study will be available from the corresponding authors upon request. Supporting Information Filename Description dme70223-sup-0001-DataS1.pdfPDF document, 122 B Data S1.
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