Kajus Merkevicius on Muck Rack

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Articles

Integrity assay for messenger RNA in mouse and human brain samples and synaptosomal preparations

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By Daina Bujanauskiene, Kajus Merkevicius, Ugne Kuliesiute, Jaroslav Denkovskij
| biorxiv.org
Abstract Traditionally, RNA integrity evaluation is based on ribosomal RNAs (rRNAs). Nevertheless, gene expression studies are usually focused on protein coding messenger RNAs (mRNAs). As rRNA and mRNA have significant structural and functional differences, the assumption that rRNA integrity properly represents mRNA integrity may not be accurate.
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