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Kalyan Sankar on Muck Rack

Kalyan Sankar

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Articles

Distinct differentiation trajectories leave lasting impacts on gene regulation and function of V2a neurons

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By Nicholas H Elder, Alireza Majd, Andrius Cesiulis, Emily A. Bulger, Ryan Samuel, Lyandysha Zholudeva, Todd C McDevitt, Faranak Fattahi, Spencer Nyarady, Kalyan Sankar
| Nature Verified
Abstract V2a interneurons are excitatory neurons found throughout the hindbrain and spinal cord, two regions that arise from distinct progenitors during embryonic development. Whether this lineage difference shapes mature gene regulation and function is unknown. V2a neurons show plasticity after spinal cord injury and are candidates for cell therapy.
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