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Articles

Interdependence of linkage disequilibrium, chromatin architecture and compositional genome organization of mammals

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By Kamel Jabbari, Johannes Wirtz, Martina Rauscher, Thomas Wiehe
| BioRxiv
Interdependence of linkage disequilibrium, chromatin architecture and compositional genome organization of mammals Kamel Jabbari, Johannes Wirtz, Martina Rauscher, Thomas Wiehe bioRxiv 293837; doi: https://doi.org/10.1101/293837
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An Isochore Framework Underlies Chromatin Architecture

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By Roma Tre, Kamel Jabbari, Giorgio Bernardi, Viale Marconi
| PLOS
The isochores/TADs comparison of mouse chromosomes indicated a good degree of match between the boundaries of TADs and the boundaries of the corresponding isochores or short isochore blocks, as outlined in Fig 1A for chromosome 17. In the case of GC-poor isochores, the correspondence not only concerned the self-interactions and the short-range interaction frequencies on the diagonal of the contact frequency matrix, but also the long-range ones along the two major axes.
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