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Kandace Gollomp on Muck Rack

Kandace Gollomp

As seen in: Frontiers, BioRxiv
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Articles

C-reactive protein and the menstrual cycle in females with sickle cell disease

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By Jessica Wu, Veronica Bochenek, Kandace Gollomp, Andrea H. Roe
| BioRxiv
Abstract There are notable sex disparities in the frequency and severity of vaso-occlusive pain episodes (VOEs) in sickle cell disease (SCD), with females experiencing more frequent and severe episodes during the reproductive years. Many individuals report a temporal link between VOEs and the menstrual cycle, suggesting that sex hormones may play a role in modulating inflammation and pain.
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Platelet factor 4 improves survival in a murine model of antibiotic-susceptible and methicillin-resistant Staphylococcus aureus peritonitis

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By Floriana Campanile, Alex Hopke, Kandace Gollomp
| Frontiers
Introduction Platelet factor 4 (PF4) is an abundant small (7.8. kDa) cationic protein stored in mammalian platelet α-granules, accounting for ~2% of the total granular content. PF4 is released from activated platelets at sites of vascular injury and mostly trapped inside platelet-rich blood clots where its concentration has been estimated to be 280 µM, over 100-fold greater than serum levels (Kowalska et al., 2010).
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