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Kansuke Koyama on Muck Rack

Kansuke Koyama

As seen in: Journal of Intensive Care
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Articles

Transient hyperlactatemia during intravenous administration of glycerol: a prospective observational study

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By Shinshu Katayama, Ken Tonai, Kansuke Koyama, Yuya Goto
| Journal of Intensive Care Verified
The present study revealed that intravenous glycerol treatment increased the lactate levels in all patients, and 84.6% of these patients developed lactate levels of > 2.0 mmol/L. This study also revealed that lactate levels differed significantly according to the duration of glycerol infusion. However, intravenous mannitol treatment did not influence the lactate levels, and there were no inter-group differences in cardiac output and stroke volume parameters.
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Time course of immature platelet count and its relation to thrombocytopenia and mortality in patients with sepsis

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By Kansuke Koyama, Shinshu Katayama, Tomohiro Muronoi, Ken Tonai
| PLOS
Of the 205 patients included, 61 (29.8%) developed severe thrombocytopenia. On admission, AIPC did not differ among the four groups. In patients with severe thrombocytopenia, AIPC decreased significantly from days 2 to 7, but remained within or above the normal range in the other three groups (overall group comparison, P<0.0001).
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Single measurement of plasminogen activator inhibitor-1 in sepsis: is it useful for evaluating the severity or prognosis of sepsis?

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By Shin Nunomiya, Kansuke Koyama
| Journal of Intensive Care Verified
We read with interest the retrospective analysis by Hoshino and colleagues on prognostic biomarkers in patients with sepsis [1]. These authors evaluated various biomarkers of sepsis and coagulation/fibrinolysis markers in adult patients with sepsis. They showed that plasminogen activator inhibitor-1 (PAI-1) was the only independent predictive marker of 28-day mortality.
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