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Karina E. Barbazuk on Muck Rack

Karina E. Barbazuk

As seen in: Frontiers in Immunology
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Impaired immune surveillance exposes the germinal center as a niche for gammaherpesvirus-associated B cell lymphomagenesis

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By Natalie Martinez, Brett Hoffman, Vasiliki Apostolou, April Feswick, Vijay K. Sirohi, Yiping Wang, Mehmet KARA Verified, Manu Nair, Rolf Renne, Erik K. Flemington, Genevieve M. Crane, Scott A. Tibbetts, Karl J. Ensberg, Mikayla S. Manzi, Karina E. Barbazuk
| Frontiers in Immunology
Abstract Background: Gammaherpesviruses establish lifelong latency in B cells and are linked to multiple human lymphoid malignancies, including Epstein-Barr virus (EBV)–associated lymphomas that arise at significantly increased frequency in settings of impaired immune surveillance. However, the cellular origins and evolutionary pathways of gammaherpesvirus-associated lymphomas remain incompletely defined.
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