Karsen E. Shoger on Muck Rack

Karsen E. Shoger

As seen in: Science Magazine
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Articles

Predicting gene level sensitivity to JAK-STAT signaling perturbation using a mechanistic-to-machine learning framework

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By Neha Cheemalavagu, Karsen E. Shoger, Yuqi Cao, Brandon A Michalides
| biorxiv.org
Thank you for your interest in spreading the word about bioRxiv. NOTE: Your email address is requested solely to identify you as the sender of this article. Your Email * Your Name * Send To * Enter multiple addresses on separate lines or separate them with commas. Message Subject (Your Name) has forwarded a page to you from bioRxiv Message Body (Your Name) thought you would like to see this page from the bioRxiv website.
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CISH attenuates homeostatic cytokine signaling to promote lung-specific macrophage programming and function

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By Cara C. Rada, Amy Baek, Neha Cheemalavagu, Karsen E. Shoger
| Science Magazine Verified
Karsen E. Shoger https://orcid.org/0000-0002-1894-7361, Neha Cheemalavagu https://orcid.org/0000-0002-5947-8864, Yuqi M. Cao, Brandon A. Michalides https://orcid.org/0000-0001-5720-8644, Virendra K. Chaudhri https://orcid.org/0000-0003-3528-4667, Jonathan A. Cohen, Harinder Singh https://orcid.org/0000-0002-6330-8526, and Rachel A.
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A role for lipid transporters in PDAC

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By Cara C. Rada, Karsen E. Shoger, Amy Baek
| Science Magazine Verified
Abstract Highlighted Articles Abstract ApoE mediates immune suppression in pancreatic ductal adenocarcinoma. Pancreatic ductal adenocarcinoma (PDAC) is marked by a fibroinflammatory, immunosuppressive microenvironment enriched with tumor-associated macrophages (TAMs). Secreted by hepatocytes and macrophages, Apolipoprotein E (ApoE) is an important regulator of plasma lipids and mediates lipid transport by binding to cell-surface lipoprotein receptors.
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