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Kateryna Shkarina on Muck Rack

Kateryna Shkarina

As seen in: Science Magazine, eLife
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Articles

Western lifestyle linked to maladaptive trained immunity

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By Kateryna Shkarina, Theresa Wagner, Aurelia Josephine Merbecks, Christabel Mennicken
| eLife
Introduction Immune responses need to be dynamic and capable of adjusting to the context in which immune stimuli are encountered. The cellular responses towards stimuli include classical activation, priming, tolerance, and trained immunity (TI) (Netea and Joosten, 2024). Upon classical activation, the antimicrobial capacity of immune cells is used to resolve an immediate threat.
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Optogenetic Induction of Pyroptosis, Necroptosis, and Apoptosis in Mammalian Cell Lines

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By Kateryna Shkarina, Petr Broz
| nlm.nih.gov
Save citation to file Format: Add to My Bibliography Your saved search Name of saved search: Search terms: Frequency: Which day? Which day? Report format: Send at most: Send even when there aren't any new results Optional text in email: Create a file for external citation management software
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The Opto-inflammasome in zebrafish as a tool to study cell and tissue responses to speck formation and cell death

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By Kateryna Shkarina, Jingwei Xiong, Bruno Reversade, Shivani S Dharmadhikari
| eLife
Our results demonstrate that Opto-ASC is an efficient tool to induce inflammasome formation and ASC-dependent cell death in zebrafish. Compared to over-expression of ASC in our earlier studies (Kuri et al., 2017), or infection models (Forn-Cuní et al., 2019), it allows a more precise spatial and temporal manipulation of inflammasome activation and cell death.
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