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Katherine Barondeau on Muck Rack

Katherine Barondeau

As seen in: BioRxiv
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TRMT1L-catalyzed m22G27 on tyrosine tRNA is required for efficient mRNA translation and cell survival under oxidative stress.

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By Han Liao, Xinyi Han, Sseu-Pei Hwang, Katherine Barondeau
| BioRxiv
Abstract Mapping of the epitranscriptome has revealed the chemical diversity of RNA modifications and their functional importance in regulating gene expression. Transfer RNAs (tRNAs) are one of the most modified cellular RNAs, containing on average 10-13 modifications per molecule. These modifications have been shown to be critical for several aspects of tRNA functions, such as decoding, folding, and stability.
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