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Genetic etiologies and diagnostic methods for congenital ventriculomegaly and hydrocephalus: A scoping review
1 INTRODUCTION Hydrocephalus arises from an imbalance in production, flow, or absorption of cerebrospinal fluid (CSF) in the ventricles of the brain (Kousi & Katsanis, 2016; McAllister, 2012). If untreated, subsequent ventricular dilation and increased intracranial pressure resulting from CSF buildup can lead to brain malformations, neurocognitive deficits, progressive macrocephaly, and even death (Kousi & Katsanis, 2016; McAllister, 2012; Zhang et al., 2006).
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