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Katie L. Burnham on Muck Rack

Katie L. Burnham

As seen in: Nature, Wiley Online Library, Thorax, Genome Medicine, Science Magazine, BioRxiv, The American Journal of Human Genetics, The Lancet, EIN News, medRxiv and
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Articles

Context-specific regulatory genetic variation in MTOR dampens neutrophil-T cell crosstalk in pneumonia-associated sepsis - Nature Communications

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By Ping Zhang, Patrick MacLean, Alicia Jia, Alice Allcock, Bora Ozcan, Roman M. Doll, Kiki Cano-Gamez, Hanyu Qin, Giuseppe Scozzafava, Andrew Brown, James Davies Verified, Amanda Chong, Alexander J. Mentzer, Katie L. Burnham, Emma Davenport, Julian Knight, Callum R. O’Neill, Ethan Prince, Imogen Dyne, Chloe Wainwright
| Nature Verified
Abstract Sepsis is a heterogeneous clinical syndrome with a high mortality, requiring personalised stratification strategies. Here, we characterise genetic variation that modulates MTOR, a critical regulator of metabolism and immune responses in sepsis. The effects are context specific, involving a regulatory element that affects MTOR expression in activated T cells with opposite effect in neutrophils.
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A consensus blood transcriptomic framework for sepsis - Nature Medicine

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By Brendon P. Scicluna, Katie L. Burnham, Andrew Moore, Soumen Khan, Charles Hinds, Olaf L. Cremer, Purvesh Khatri, Timothy E. Sweeney, Julian Knight
| Nature Verified
Abstract Sepsis is a life-threatening condition driven by a maladaptive host response to infection. To establish a standardized blood transcriptomic subtype model, we aggregated blood transcriptomics data from two major sepsis cohorts: the Molecular Diagnosis and Risk Stratification of Sepsis (MARS) project (n = 678 sampled on intensive care unit admission; ClinicalTrials.gov registration no.
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Great Lakes Orthopaedic Center Improving Patients’ Overall Health in Northern Michigan with Prescribe FIT

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By Katie L. Burnham
| EIN News
Great Lakes Orthopaedic Center Improving Patients’ Overall Health in Northern Michigan with Prescribe FIT Great Lakes Orthopedic Center + Prescribe FIT Prescribe FIT PACE Mobile App Through Prescribe FIT, GLOC empowers patients to reduce MSK pain, boost mobility, and achieve lasting health beyond the clinic walls. I went to Dr. Anderson because I was in pain and needed a double hip replacement.
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