Kave Moloudi

1 INTRODUCTION Hypoxia is considered as a hallmark in solid tumors and is fundamental to regulating physiological events and cell signaling. Furthermore, hypoxia in the tumor microenvironment causes resistance to treatment, for instance, Photodynamic therapy (Muz et al., 2015; Ruan et al., 2009).

Skip to main page content Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation Save citation to file Format: Add to My Bibliography Your saved search Name of saved search: Search terms: Frequency: Which day? Which day? Report format: Send at most: Send even when there aren't any new results Optional text in email: Create a file for external citation management software Display options Abstract Cell cycle arrest (CCA) is seen as a prime candidate for effective cancer therapy.

1. Introduction Photodynamic therapy (PDT) has been clinically approved as a relatively safe and effective treatment option for certain types of cancer as well as noncancerous skin conditions such as psoriasis, acne, and infections.